Results 161 to 170 of about 47,553 (291)

Impacts of conventional and high-oleic soybean oil supplementation on rumen microbiology, physiology, immunity, and growth of recently weaned Brangus steers. [PDF]

Transl Anim Sci
Vedovatto M, Marcon H, Ferreira MFL, Edwards AK, Chinaglia JV, Leite GP, Harvey KM, Laubinger B, Dos Reis BR.   +8 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Impacts of Sprouted Barley on Performance and Carcass Ultrasound Measurements in Angus-Influenced Steers During Backgrounding. [PDF]

Animals (Basel)
Crump ZC, Alberto AF, Brown BL, Roholt BW, Okamoto LL, Spurling RA, Ward RE, Blackett BM, Harding RL, Ranathunga SD, Thornton KJ.   +10 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Microbiome Responses of Beef Steers to Rotational Grazing of Toxic Endophyte-Infected Tall Fescue Under Fall Conditions. [PDF]

Animals (Basel)
Llada IM, Lourenco JM, Dycus MM, Lamichhane U, Ross MK, Suen G, Jones DP, Hill NS, Filipov NM.   +8 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Effects of anthelmintics and gastrointestinal nematode infection intensity on growth and production performance and carcass quality in western Canadian feedlot cattle. [PDF]

Transl Anim Sci
De Seram EL, Penner GB, Campbell JR, Parker SE, Gilleard JS, Pollock CM, Ekanayake S, Uehlinger FD.   +7 more
europepmc   +1 more source

Two steers

, 1980
A photo of two clean ...

core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source