Results 31 to 40 of about 845 (253)

Patient‐Centric First‐in‐Human Dose Selection: An Ex Vivo Minimal Anticipated Biological Effect Level Approach for T‐Cell Engagers in Multiple Myeloma

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The minimal anticipated biological effect level (MABEL) approach to first‐in‐human (FIH) dose calculation can lead to long dose‐escalation periods before observing clinical activity. We used a novel ex vivo MABEL approach to calculate the FIH starting dose for forimtamig, a T‐cell bispecific antibody under investigation for the treatment of relapsed ...
Thomas E. Kraft   +16 more
wiley   +1 more source

On affine group actions on Stein manifolds

open access: yes, 2012
. We consider actions of the complex affine group Aff ( )
Helisson Coutinho
core   +1 more source

ESG Ratings and Firms' Engagement in Global Innovation Ecosystems: Implications for Green Innovation Capacity

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The increasing salience of climate change has intensified attention to the roe of ESG ratings in shaping firms' green innovation. We examine the link between ESG performance and green innovation, highlighting the role of participation in global innovation networks.
Miaomiao Tao   +3 more
wiley   +1 more source

Holomorphic convexity and Carleman approximation by entire functions on Stein manifolds [PDF]

open access: yes, 2010
We give necessary and sufficient conditions for totally real sets in Stein manifolds to admit Carleman approximation of class Ck , k ≥ 1, by entire ...
Per Erik Manne   +5 more
core   +1 more source

Insider Ownership and Investment Efficiency

open access: yesInternational Journal of Finance &Economics, EarlyView.
ABSTRACT This study examines the relationship between insider ownership and investment efficiency in Indian publicly listed firms, utilising panel data spanning 2001 to 2015. It explores how agency conflicts contribute to suboptimal capital investment decisions. Our analysis reveals that increased insider ownership is associated with reduced investment
Bibek Bhatta
wiley   +1 more source

Bayesian Model Averaging in Causal Instrumental Variable Models

open access: yesJournal of Applied Econometrics, EarlyView.
ABSTRACT Instrumental variables are a popular tool to infer causal effects under unobserved confounding, but choosing suitable instruments is challenging in practice. We propose gIVBMA, a Bayesian model averaging procedure that addresses this challenge by averaging across different sets of instrumental variables and covariates in a structural equation ...
Gregor Steiner, Mark Steel
wiley   +1 more source

Nonlinear Calderón Problem on Stein Manifolds

open access: yes, 2021
This thesis is devoted to the study of inverse problems for semilinear elliptic equations on Stein manifolds with Kähler metric. After developing some preliminary techniques, we will show that the Dirichlet-Neumann maps for certain semilinear elliptic ...
Ma, Yilin
core  

Non-algebraic examples of manifolds with the volume density property [PDF]

open access: yes, 2017
Some Stein manifolds (with a volume form) have a large group of (volume-preserving) automorphisms: this is formalized by the (volume) density property, which has remarkable consequences.
Ramos Peon, Alexandre
core   +1 more source

Age‐related local versus systemic early phase wound healing dynamics following free gingival graft harvest

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Free palatal gingival grafts (FGG) are commonly harvested during mucogingival procedures. The present study investigates age‐related local and systemic early secondary wound healing outcomes, following FGG harvest in a rat model. Methods A 4.2 mm diameter defect was created in the palate of 24 younger (2 m) and 24 older (6 m) Wistar
Maayan Atzmon‐Shavit   +3 more
wiley   +1 more source

Density Property of Stein Manifolds and Holomorphic Matrix Factorization [PDF]

open access: yes
We present results on the density property of Stein manifolds and on factorization of holomorphic matrices. A Stein manifold with the density property has an infinite dimensional group of holomorphic automorphisms.
Huang, Gaofeng
core   +1 more source

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