Results 151 to 160 of about 876,778 (355)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Stellar pulsation and the abundance of helium

open access: yesThe Astrophysical Journal, 1978
It has been suggested that the appearance of nonvariable stars within the Cepheid strip could be explained by a range in the helium abundance of Population I stars. In order to study this possibility, spectra were obtained of the main-sequence B stars in the galactic cluster NGC 129, which contains a nonvariable Cepheid-strip star, and M25, which ...
openaire   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Carbon and oxygen in HII regions of the Magellanic Clouds: abundance discrepancy and chemical evolution

open access: yes, 2017
We present C and O abundances in the Magellanic Clouds derived from deep spectra of HII regions. The data have been taken with the Ultraviolet-Visual Echelle Spectrograph at the 8.2-m VLT. The sample comprises 5 HII regions in the Large Magellanic Cloud (
Bresolin, F.   +7 more
core   +1 more source

Observations of the Ultraviolet-bright Star III-60 in the Globular Cluster NGC 6723

open access: yesThe Astrophysical Journal
We have analyzed archival far-ultraviolet spectra of the UV-bright star III-60 in the globular cluster NGC 6723 obtained with the Far Ultraviolet Spectroscopic Explorer and the Cosmic Origins Spectrograph. We find that the star's photospheric parameters (
William V. Dixon
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Stellar Composition from Narrow-Band Photometry - IV: CALCIUM ABUNDANCES IN G AND K GIANTS [PDF]

open access: bronze, 1972
MARIA EDUARDA PINTO MARQUES NEIVA RÊGO   +2 more
openalex   +1 more source

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