Results 151 to 160 of about 64,475 (321)

The Stellar Abundances and Galactic Evolution Survey (SAGES). IV. Surface Gravity Estimation and Giant–Dwarf Separation with the DDO51 Filter

The Astrophysical Journal
Reliable estimation of stellar surface gravity (log g ) for a large sample is crucial for evaluating stellar evolution models and understanding galactic structure; however, it is not easy to accomplish due to the difficulty in gathering a large ...
Qiqian Zhang, Zhou Fan, Gang Zhao, Ying Wu, Wei Wang, Kai Xiao, Hongrui Gu, Jie Zheng, Jingkun Zhao, Chun Li, Yuqin Chen, Haibo Yuan, Haining Li, Kefeng Tan, Yihan Song, Ali Luo, Nan Song, Yujuan Liu, Yaqian Wu   +18 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Iron Snails: Nonequilibrium Dynamics and Spiral Abundance Patterns

The Astrophysical Journal
Galaxies are not in a dynamical steady state: they continually undergo perturbations, e.g., from infalling dwarf galaxies and dark matter substructure. After a dynamical perturbation, stars phase mix toward a new steady state; in so doing, they generally
Neige Frankel, David W. Hogg, Scott Tremaine, Adrian Price-Whelan, Jeff Shen   +4 more
doaj   +1 more source

938,720 Giants from LAMOST I: Determination of Stellar Parameters and α, C, N Abundances with Deep Learning [PDF]

, 2019
X. Zhang, Gang Zhao, Chengqun Yang, Q. X. Wang, Wenbo Zuo   +4 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Chemical Abundances in the Leiptr Stellar Stream: A Disrupted Ultra-faint Dwarf Galaxy?

The Open Journal of Astrophysics
Chemical abundances of stellar streams can be used to determine the nature of a stream's progenitor. Here we study the progenitor of the recently discovered Leiptr stellar stream, which was previously suggested to be a tidally disrupted halo globular ...
Kaia R. Atzberger, Sam A. Usman, Alexander P. Ji, Lara R. Cullinane, Denis Erkal, Terese T. Hansen, Geraint F. Lewis, Ting S. Li, Guilherme Limberg, Alice Luna, Sarah L. Martell, Madeleine McKenzie, Andrew B. Pace, Daniel B. Zucker   +13 more
doaj   +1 more source

Ages and abundances in large-scale stellar discs of nearby S0 galaxies [PDF]

, 2012
О. К. Сильченко, I. S. Proshina, A. P. Shulga, S. E. Koposov   +3 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Observations of the Ultraviolet-bright Star ZNG 1 in the Globular Cluster M5 (NGC 5904)

The Astronomical Journal
We have analyzed archival spectra of the hot UV-bright star ZNG 1 in the globular cluster M5 (NGC 5904) obtained with the Far Ultraviolet Spectroscopic Explorer and the Space Telescope Imaging Spectrograph.
William V. Dixon
doaj   +1 more source