Results 201 to 210 of about 876,778 (355)

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause   +6 more
wiley   +1 more source

Revisiting the Li Abundances of Stars with and without Detected Planets from High-resolution Spectroscopy

open access: yesThe Astrophysical Journal
Whether the presence of planets affects the lithium (Li) abundance of their host stars is still an open question. To investigate the difference in the Li abundance between planet-host stars (HSs) and isolated stars (ISs) with no detected planets, we ...
Jinxiao Qin   +14 more
doaj   +1 more source

Stellar parameters and abundances [PDF]

open access: yesProceedings of 11th Symposium on Nuclei in the Cosmos — PoS(NIC XI), 2011
openaire   +1 more source

Not just a by‐product: circular DNA molecules derived from V(D)J recombination are linked to worse prognosis in B‐cell leukemia

open access: yesMolecular Oncology, EarlyView.
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley   +1 more source

Chemical Diversity on Small Scales: Abundance Analysis of the Tucana V Ultrafaint Dwarf Galaxy

open access: yesThe Astrophysical Journal
The growing number of Milky Way satellites detected in recent years has introduced a new focus for stellar abundance analysis. Abundances of stars in satellites have been used to probe the nature of these systems and their chemical evolution.
Terese T. Hansen   +7 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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