Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao +7 more
wiley +1 more source
Neutron capture measurements for s-process nucleosynthesis: A review about CERN n_TOF developments and contributions. [PDF]
Domingo-Pardo C +145 more
europepmc +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Helioseismic inference of the solar radiative opacity. [PDF]
Buldgen G +20 more
europepmc +1 more source
An overall picture of EMP stars using the stellar abundances for galactic archaeology (SAGA) database [PDF]
Takuma Suda +7 more
openalex +1 more source
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti +8 more
wiley +1 more source
A Novel Hybrid High-Speed Mass Spectrometer Allows Rapid Translation From Biomarker Candidates to Targeted Clinical Tests Using <sup>15</sup>N-Labeled Proteins. [PDF]
Wahle M +11 more
europepmc +1 more source
Stellar abundance analyses in the light of 3D hydrodynamical model atmospheres
M. Asplund
openalex +2 more sources
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
History of individual presolar SiC grains revealed by stellar winds. [PDF]
Bajo KI +4 more
europepmc +1 more source

