Results 31 to 40 of about 1,058 (213)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Stellar abundances tracing the formation of the Galactic Bulge [PDF]

Proceedings of the International Astronomical Union, 2008
AbstractThe metallicity distribution and abundance ratios of the Galactic bulge are reviewed. Issues raised by different groups in recent work, in particular the high metallicity end, a comparison between the oxygen abundances derived from different indicators, the [OI] 630nm and IR OH lines, and the issue of measuring giants vs. dwarfs, are discussed.
Barbuy, Beatriz, Zoccali, Manuela, Ortolani, Sergio, Hill, Vanessa, Renzini, Alvio, Meléndez, Jorge, Gómez, Anita, Asplund, Martin, Minniti, Dante, Bica, Eduardo, Alves-Brito, Alan   +10 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Abundance of Helium in Stellar Atmospheres [PDF]

Highlights of Astronomy, 1971
Helium abundance in stellar atmospheres has been the subject of several recent investigations, essentially induced by progresses in the computation of non-grey model atmospheres (including line blanketing in the far U.V.), by considerable advances in the theory of Stark broadening of helium lines, by non local thermodynamic equilibrium (LTE) work for ...
openaire   +1 more source

Stellar Iron Abundances: Non‐LTE Effects [PDF]

The Astrophysical Journal, 1999
22 pages, 9 figures, 1 table, ApJ style ...
Thevenin, F., Idiart, T. P.
openaire   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Stellar photospheric abundances as a probe of discs and planets [PDF]

Monthly Notices of the Royal Astronomical Society, 2018
Protoplanetary disks, debris disks, and disrupted or evaporating planets can all feed accretion onto stars. The photospheric abundances of such stars may then reveal the composition of the accreted material. This is especially likely in B to mid-F type stars, which have radiative envelopes and hence less bulk--photosphere mixing.
Adam S Jermyn, Mihkel Kama
openaire   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

THE RAVE CATALOG OF STELLAR ELEMENTAL ABUNDANCES: FIRST DATA RELEASE [PDF]

The Astronomical Journal, 2011
We present chemical elemental abundances for $36,561$ stars observed by the RAdial Velocity Experiment (RAVE), an ambitious spectroscopic survey of our Galaxy at Galactic latitudes $|$b$|>25^{\circ}$ and with magnitudes in the range 9$
Zwitter, Tomaž, Ruchti, Gregory R., Bienaymé, Olivier, Bland-Hawthorn, Joss Bland, Campbell, Randy D., Freeman, Kenneth C., Gibson, Brad K., Gilmore, Gerard F., Boeche, Corrado, Siebert, Arnaud, Williams, Mary E K, De Jong, Roelof S., Steinmetz, Matthias, Fulbright, Jon P., Grebel, Eva K., Helmi, Amina, Munari, Ulisse, Navarro, Julio F., Parker, Quentin A., Reid, Warren A., Seabroke, George M., Siviero, Alessandro, Watson, Fred G., Wyse, Rosemary F G   +23 more
openaire   +6 more sources