Results 251 to 260 of about 2,560 (288)

V3101 Cyg: A Cataclysmic Variable Born with a Brown Dwarf Donor

Ramirez S, Gänsicke B, Sahu S, Belloni D, Pala A, Koester D, Toloza O, Lagos-Vilches F.   +7 more
europepmc   +1 more source

Fundamentals of Interior Modelling and Challenges in the Interpretation of Observed Rocky Exoplanets. [PDF]

Space Sci Rev
Baumeister P, Miozzi F, Guimond CM, Steinmeyer ML, Dorn C, Karato SI, Bolmont É, Revol A, Thamm A, Noack L.   +9 more
europepmc   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Massive extended streamers feed high-mass young stars. [PDF]

Sci Adv
Olguin FA, Sanhueza P, Ginsburg A, Chen HV, Tanaka KEI, Lu X, Morii K, Nakamura F, Li S, Cheng Y, Zhang Q, Luo Q, Oya Y, Sakai T, Saito M, Guzmán AE.   +15 more
europepmc   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

A hot white dwarf merger remnant revealed by an ultraviolet detection of carbon. [PDF]

Nat Astron
Sahu S, Bédard A, Gänsicke BT, Tremblay PE, Koester D, Farihi J, Hermes JJ, Hollands MA, Cunningham T, Redfield S.   +9 more
europepmc   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Lense-Thirring precession after a supermassive black hole disrupts a star. [PDF]

Nature
Pasham DR, Zajaček M, Nixon CJ, Coughlin ER, Śniegowska M, Janiuk A, Czerny B, Wevers T, Guolo M, Ajay Y, Loewenstein M.   +10 more
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source