Results 41 to 50 of about 2,560 (288)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Observational clues to the physics at the magnetosphere in young stellar objects
EPJ Web of Conferences, 2014 Classical T Tauri stars offer an excellent laboratory to study the accretion process and star-disk interaction, which define the transfer of mass and angular momentum in the system. The interaction takes place very close to the star, in a region of about
Alencar Silvia H. P.
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Semi-analytical Model for Stellar Evolution in AGN Disks
The Astrophysical JournalDisks of gas accreting onto supermassive black holes may host numerous stellar-mass objects, formed within the disk or captured from a nuclear star cluster.
Alexander J. Dittmann, Matteo Cantiello
doaj +1 more source
Disk accretion onto a magnetized star
EPJ Web of Conferences, 2014 The problem of interaction of the rotating magnetic field, frozen to a star, with a thin well conducting accretion disk is solved exactly. It is shown that a disk pushes the magnetic field lines towards a star, compressing the stellar dipole magnetic ...
Istomin Ya. N., Haensel P.
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The Astrophysical JournalMagnetospheric accretion is a key process that shapes the inner disks of T Tauri stars, controlling mass and angular momentum evolution. It produces strong ultraviolet and optical emission that irradiates the planet-forming environment.
Caeley V. Pittman +22 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Formation of Massive and Wide First-star Binaries in Radiation Hydrodynamic Simulations
The Astrophysical Journal, 2023 We study the formation of Population III stars by performing radiation hydrodynamic simulations for three different initial clouds extracted from cosmological hydrodynamic simulations.
Kazuyuki Sugimura +4 more
doaj +1 more source