Results 241 to 250 of about 41,311 (309)

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

A high-velocity star recently ejected by an intermediate-mass black hole in M15. [PDF]

Natl Sci Rev
Huang Y, Li Q, Liu J, Dong X, Zhang H, Lu Y, Du C.   +6 more
europepmc   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Vibrationally-dependent molecular dynamics in mutual neutralisation reactions of molecular oxygen ions. [PDF]

Nat Commun
Poline M, Dochain A, Rosén S, Ji M, Cederquist H, Zettergren H, Schmidt HT, Larsson M, Ard SG, Shuman NS, Viggiano AA, Thomas RD.   +11 more
europepmc   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

High-temperature ²⁰⁵Tl decay clarifies ²⁰⁵Pb dating in early Solar System. [PDF]

Nature
Leckenby G, Sidhu RS, Chen RJ, Mancino R, Szányi B, Bai M, Battino U, Blaum K, Brandau C, Cristallo S, Dickel T, Dillmann I, Dmytriiev D, Faestermann T, Forstner O, Franczak B, Geissel H, Gernhäuser R, Glorius J, Griffin C, Gumberidze A, Haettner E, Hillenbrand PM, Karakas A, Kaur T, Korten W, Kozhuharov C, Kuzminchuk N, Langanke K, Litvinov S, Litvinov YA, Lugaro M, Martínez-Pinedo G, Menz E, Meyer B, Morgenroth T, Neff T, Nociforo C, Petridis N, Pignatari M, Popp U, Purushothaman S, Reifarth R, Sanjari S, Scheidenberger C, Spillmann U, Steck M, Stöhlker T, Tanaka YK, Trassinelli M, Trotsenko S, Varga L, Vescovi D, Wang M, Weick H, Yagüe Lopéz A, Yamaguchi T, Zhang Y, Zhao J.   +58 more
europepmc   +1 more source

Burn‐Safe Biodegradable Magnetocaloric Composites for Temperature‐Controlled Biomedical Applications

Advanced Science, EarlyView.
This work investigates a magnetocaloric (Mn,Fe)2(P,Si) compound tailored for precise, self‐regulating heating in biomedical use. With a Curie temperature tuned at 43 °C, it enables therapeutic activation without overheating. Encapsulation in a composite ensures controlled temperature rise under an alternating magnetic field (AMF), with high ...
Pornpawee Uliss, Vasiliki Gkouzioti, Wuliji Hanggai, Friso Kahler, Elena Aprea, Qi Jia, Jean‐Philippe Frimat, Ekkes Brück, Clementine M. Boutry   +8 more
wiley   +1 more source

Physicochemical Controls on the Compositions of the Earth and Planets. [PDF]

Space Sci Rev
Sossi PA, Hin RC, Kleine T, Morbidelli A, Nimmo F.   +4 more
europepmc   +1 more source

Artificial Tactile Perception System for Exploring Internal and External Features of Objects via Time‐Frequency Features

Advanced Science, EarlyView.
By engaging in different active exploration behaviors, the tactile perception system can generate distinct signal modes, enabling the application of targeted decoding strategies for efficient and accurate perception of both external and internal object features.
Yuanzhi Zhou, Jingqi Zhang, Linyi Li, Muxing Huang, Ziyi Zhang, Xingmin Lu, Zilan Li, Xuchun Gui, Xinming Li   +8 more
wiley   +1 more source

<i>In situ</i> analysis of titanium isotope ratios in stardust using LA-CC-MC-ICPMS/MS.

J Anal At Spectrom
Shaw KMM, Pfeifer M, Coath BLL, Lewis J, Bevan D, Coath CD, Elliott T.   +6 more
europepmc   +1 more source