Results 51 to 60 of about 41,311 (309)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
, 2007 The rate of accretion of matter from a solar-type star onto a primordial black hole (PBH) that passes through it is calculated. The probability that a PBH is captured into an orbit around a star in a galaxy is found.
A. A. Shatskii +3 more
core +1 more source
Two-Dimensional Stellar Collisions
The Astrophysical Journal, 1968 Head-on collision between two solar type stars, discussing shock front propagation, mass flow and relativistic ...
openaire +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Modulated Gamma-ray emission from compact millisecond pulsar binary systems
, 2013 A significant amount of the millisecond pulsars has been discovered within binary systems. In several such binary systems the masses of the companion stars have been derived allowing to distinguish two classes of objects, called the Black Widow and the ...
Bednarek, W.
core +1 more source
Stellar Collisions and Blue Straggler Formation
, 2001 We review recent 3D hydrodynamic calculations of stellar collisions using the Smoothed Particle Hydrodynamics (SPH) method, and we discuss the implications of the results for the formation and evolution of blue stragglers in globular clusters. We also discuss the construction of simple analytic models for merger remnants, approximating the mass loss ...
Lombardi, James C., Rasio, Frederic A.
openaire +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The Primary Flare Following a Stellar Collision in a Galactic Nucleus
The Astrophysical Journal LettersHigh-velocity stellar collisions near supermassive black holes may result in a complete disruption of the stars. The initial disruption can have energies on par with supernovae and power a very fast transient.
Yuval Brutman +2 more
doaj +1 more source
Atomic data from the IRON project - LI. Electron impact excitation of FeIX [PDF]
, 2002 We calculate collision strengths and thermally averaged collision strengths for electron excitation between the one hundred and forty energetically lowest levels of Fe8+.
Le Dourneuf, M, Storey, PJ, Zeippen, CJ
core