Results 31 to 40 of about 4,432 (267)
Stream Members Only: Data-driven Characterization of Stellar Streams with Mixture Density Networks
Stellar streams are sensitive probes of the Milky Way’s gravitational potential. The mean track of a stream constrains global properties of the potential, while its fine-grained surface density constrains galactic substructure. A precise characterization
Nathaniel Starkman +6 more
doaj +1 more source
Clusters are excellent test benches for verification and improvement of stellar evolution theory. The recent detection of solar-like oscillations in G-K giants in the open cluster NGC6819 with Kepler provides us with independent constraints on the masses
Lagarde, N +4 more
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Pulsating stars are universally recognized as precise distance indicators and tracers of stellar populations. Their variability, combined with well-defined relationships between pulsation properties and intrinsic evolutionary parameters such as ...
Giulia De Somma +3 more
doaj +1 more source
Young stellar distance indicators and the extragalactic distance scale
Invited review at 2022 RR Lyrae and Cepheids conference on La Palma.
openaire +2 more sources
Distance to the Brick cloud using stellar kinematics
Context.The central molecular zone at the Galactic center is currently being studied intensively to understand how star formation proceeds under the extreme conditions of a galactic nucleus. Knowing the position of molecular clouds along the line of sight toward the Galactic center has had important implications in our understanding of the physics of ...
Á. Martínez-Arranz +3 more
openaire +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

