Results 331 to 340 of about 2,843,859 (384)

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Energy calibration of the 2.5 MV Pelletron at the Dalton Cumbrian Facility. [PDF]

Eur Phys J A Hadron Nucl
Linkowski K, Sidhu RS, Skowronski J, Aliotta M, Black P, Davinson T, Wiescher M, Caciolli A, Jones J, Manukyan K, Robertson D, Smith A.   +11 more
europepmc   +1 more source

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Molecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source

Enhanced production of ⁶⁰Fe in massive stars. [PDF]

Nat Commun
Spyrou A, Richman D, Couture A, Fields CE, Liddick SN, Childers K, Crider BP, DeYoung PA, Dombos AC, Gastis P, Guttormsen M, Hermansen K, Larsen AC, Lewis R, Lyons S, Midtbø JE, Mosby S, Muecher D, Naqvi F, Palmisano-Kyle A, Perdikakis G, Prokop C, Schatz H, Smith MK, Sumithrarachchi C, Sweet A.   +25 more
europepmc   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The ²²Ne( α ,n)²⁵Mg reaction - state of the art, astrophysics, and perspectives. [PDF]

Eur Phys J A Hadron Nucl
Best A, Adsley P, Amberger R, Battino U, Chillery T, La Cognata M, deBoer RJ, Mercogliano D, Ota S, Rapagnani D, Sidhu RS, Spartà R, Tumino A, Wiescher M.   +13 more
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

A luminous and young galaxy at z = 12.33 revealed by a JWST/MIRI detection of Hα and [O iii]. [PDF]

Nat Astron
Zavala JA, Castellano M, Akins HB, Bakx TJLC, Burgarella D, Casey CM, Chávez Ortiz ÓA, Dickinson M, Finkelstein SL, Mitsuhashi I, Nakajima K, Pérez-González PG, Arrabal Haro P, Bergamini P, Buat V, Backhaus B, Calabrò A, Cleri NJ, Fernández-Arenas D, Fontana A, Franco M, Grillo C, Giavalisco M, Grogin NA, Hathi N, Hirschmann M, Ikeda R, Jung I, Kartaltepe JS, Koekemoer AM, Larson RL, McKinney J, Papovich C, Rosati P, Saito T, Santini P, Terlevich R, Terlevich E, Treu T, Yung LYA.   +39 more
europepmc   +1 more source

A binary merger product as the direct progenitor of a Type II-P supernova

Niu* Z, Sun* N, Zapartas* E, Souropanis D, Cui Y, Maund JR, Andrews JJ, Briel MM, Fraser M, Gossage S, Kruckow MU, Liotine C, Liu Z, Srivas PM, Teng E, Wang X, Yang Y, Liu J.   +17 more
europepmc   +1 more source

One month convection timescale on the surface of a giant evolved star. [PDF]

Nature
Vlemmings W, Khouri T, Bojnordi Arbab B, De Beck E, Maercker M.   +4 more
europepmc   +1 more source