Results 171 to 180 of about 1,362,486 (349)

The 300 pc Resolution Imaging of a z = 8.31 Galaxy: Turbulent Ionized Gas and Potential Stellar Feedback 600 Million Years after the Big Bang [PDF]

open access: gold, 2023
Yoichi Tamura   +18 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Inhomogeneous Reionization Regulated by Radiative and Stellar Feedbacks

open access: yes, 1999
We study the inhomogeneous reionization in a critical density CDM universe due to stellar sources, including Population III objects. The spatial distribution of the sources is obtained from high resolution numerical N-body simulations. We calculate the source properties taking into account a self-consistent treatment of both radiative (ie ionizing and ...
CIARDI B.   +3 more
openaire   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Tracing the Origins of Hot Halo Gas in Milky Way–type Galaxies with SMUGGLE

open access: yesThe Astrophysical Journal
Current galaxy formation models predict the existence of X-ray-emitting gaseous halos around Milky Way (MW)–type galaxies. To investigate properties of this coronal gas in MW-like galaxies, we analyze a suite of high-resolution simulations based on the ...
Zhijie Zhang   +10 more
doaj   +1 more source

Stellar Feedback on the Earliest Stage of Massive Star Formation [PDF]

open access: bronze, 2021
Omnarayani Nayak   +9 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The Low-redshift Lyman Continuum Survey: The Roles of Stellar Feedback and Interstellar Medium Geometry in LyC Escape

open access: yesThe Astrophysical Journal
One of the fundamental questions of cosmology is the origin and mechanism(s) responsible for the reionization of the Universe beyond z  ∼ 6. Many studies have focused on Hubble Space Telescope (HST) Cosmic Origins Spectrograph (COS) observations of local
Sophia R. Flury   +32 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

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