PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Saturn's F ring is intermittently shepherded by Prometheus. [PDF]
Cuzzi JN +4 more
europepmc +1 more source
The rings and small moons of Uranus and Neptune. [PDF]
Showalter MR.
europepmc +1 more source
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng +12 more
wiley +1 more source
Sensitivity Analysis and Impact of the Kappa-Correction of Residual Ionospheric Biases on Radio Occultation Climatologies. [PDF]
Danzer J +3 more
europepmc +1 more source
Temporal Evolution of Low-Latitude Plasma Blobs Identified From Multiple Measurements: ICON, GOLD, and Madrigal TEC. [PDF]
Park J, Huang CS, Eastes RW, Coster AJ.
europepmc +1 more source
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
Photochemical Haze Formation on Titan and Uranus: A Comparative Review. [PDF]
Dubois D.
europepmc +1 more source
UV/Vis<sup>+</sup> photochemistry database: Structure, content and applications. [PDF]
Noelle A +14 more
europepmc +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source

