Results 171 to 180 of about 373 (258)

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

Advanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu, Ziqian Yang, Arina E. Velieva, Eleanor M. Plaster, Mingyue Fan, Donia W. Ahmed, Avinava Roy, Pamela Duran, Pamela Panovich, Alexandra S. Piotrowski‐Daspit, Carlos A. Aguilar, Megan L. Killian, Claudia Loebel   +12 more
wiley   +1 more source

Evolution and Observable Properties of Rocky Planet Atmospheres. [PDF]

Space Sci Rev
Steinmeyer ML, Noack L, Baumeister P, Hamano K, Way MJ, Breuer D, Seki K, Brachmann C, Gaillard F, Scherf M, Berdyugina SV, Demory BO.   +11 more
europepmc   +1 more source

An Earth-sized exoplanet ripe for emission spectroscopy with JWST in orbit around a nearby ultracool dwarf star

, 2023
Gillon M, Pedersen P, Rackham B, Dransfield G, Ducrot E, Barkaoui K, Burdanov A, Schroffenegger U, Chew YGM, Lederer S, Alonso R, Burgasser A, Howell S, Narita N, de Wit J, Demory B, Queloz D, Triaud A, Delrez L, Jehin E, Hooton M, Garcia L, Munoz CJ, Murray C, Pozuelos F, Sebastian D, Timmermans M, Thompson S, Zuniga-Fernandez S, Aceituno J, Aganze C, Amado P, Benkhaldoun Z, Bolmont É, Clark C, Davoudi F, de Leon J, Ikoma M, Ikuta K, Isogai K, Fukuda I, Fukui A, Gerasimov R, Ghachoui M, Hayashi Y, Hu R, Kagetani T, Kawai Y, Kawauchi K, Koll D, Livingston J, Lyu X, Mori M, Murgas F, Palle E, Rebolo R, Selsis F, Sota A, Stassun K, Tamura M, Theissen C, Turbet M, Grootel VV, Varas R, Watanabe N.   +64 more
europepmc   +1 more source

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

Advanced Science, EarlyView.
TROP2 is identified as a novel tumor‐selective lysosomal‐targeting receptor with established clinical relevance. TROP2‐targeting chimeras (TRTACs) are developed by genetically fusing a TROP2‐binding nanobody to nanobodies against specific target proteins.
Luping Chen, Xinying Fu, Wenqian Dong, Xiaobei Deng, Simin Chen, Fujun Wang, Jian Zhao, Shiqun Shao, Liqiang Fan, Jingyu Zhang, Lixin Zhang   +10 more
wiley   +1 more source

Stellar occultation investigations of Pluto's atmosphere

, 2003
We investigate the shape of Pluto's atmosphere using data from the occultation of the V=15.7 star P131.1 by Pluto on 2002 Aug 21 (UT). We find that Pluto's atmosphere, as projected onto the sky, is noticeably non-circular. This implies an overall ellipsoidal shape, which could be an indication of high winds and/or latitudinal stratification.
openaire   +1 more source

Fundamentals of Interior Modelling and Challenges in the Interpretation of Observed Rocky Exoplanets. [PDF]

Space Sci Rev
Baumeister P, Miozzi F, Guimond CM, Steinmeyer ML, Dorn C, Karato SI, Bolmont É, Revol A, Thamm A, Noack L.   +9 more
europepmc   +1 more source

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

Advanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li   +7 more
wiley   +1 more source

Saturn's F ring is intermittently shepherded by Prometheus. [PDF]

Sci Adv
Cuzzi JN, Marouf EA, French RG, Murray CD, Cooper NJ.   +4 more
europepmc   +1 more source

The metal-poor atmosphere of a Neptune/Sub-Neptune planet’s progenitor

, 2023
Barat S, Desert J, Vazan A, Baeyens R, Line MR, Fortney JJ, David TJ, Livingston JH, Jacobs B, Panwar V, Shivkumar H, Todorov K, Pino L, Mraz G, Petigura E.   +14 more
europepmc   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source