Results 41 to 50 of about 346 (266)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Zonal Winds in Titan’s Middle Atmosphere from a Stellar Occultation Observed with Keck Adaptive Optics

open access: yesThe Planetary Science Journal
We present spatially resolved Keck/NIRC2 images of a stellar occultation by Titan on 2022 September 5 and compare them to predictions from concurrent Atacama Large Millimeter/submillimeter Array (ALMA) observations and a suite of general circulation ...
Theresa C. Marlin   +11 more
doaj   +1 more source

Direct comparisons of GOMOS and SAGE III NO3 vertical profiles [PDF]

open access: yesAtmospheric Measurement Techniques, 2012
In this paper, we present the first global comparisons between the two unique satellite-borne data sets of nitrogen trioxide (NO3) vertical profiles retrieved from the GOMOS (Global Ozone Monitoring by the Occultation of Stars) stellar occultations and ...
J. R. Moore   +3 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

First climatology of polar mesospheric clouds from GOMOS/ENVISAT stellar occultation instrument [PDF]

open access: yesAtmospheric Chemistry and Physics, 2010
GOMOS (Global Ozone Monitoring by Occultation of Stars), on board the European platform ENVISAT launched in 2002, is a stellar occultation instrument combining four spectrometers and two fast photometers which measure light at 1 kHz sampling rate in the ...
K. Pérot   +7 more
doaj  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Material around the Centaur (2060) Chiron from the 2018 November 28 UT Stellar Occultation

open access: yesThe Planetary Science Journal, 2023
A stellar occultation of Gaia DR3 2646598228351156352 by the Centaur (2060) Chiron was observed from the South African Astronomical Observatory on 2018 November 28 UT.
Amanda A. Sickafoose   +7 more
doaj   +1 more source

10199 Chariklo Stellar Occultation Candidates: 1999–2005 [PDF]

open access: yesThe Astronomical Journal, 2000
The Flagstaff Astrometric Scanning Transit Telescope was used to scan the sky in search of occultation candidates through which the Centaur 10199 Chariklo (formerly 1997 CU26) will pass in 1999–2005. Positions for 96,397 stars (magnitudes 7.5 < V < 17.3) were determined using differential reductions to the ACT catalog of star positions and proper ...
R. C. Stone   +3 more
openaire   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

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