Results 191 to 200 of about 42,007 (286)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

A hot-Jupiter progenitor on a super-eccentric retrograde orbit. [PDF]

Nature
Gupta AF, Millholland SC, Im H, Dong J, Jackson JM, Carleo I, Libby-Roberts J, Delamer M, Giovinazzi MR, Lin ASJ, Kanodia S, Wang XY, Stassun K, Masseron T, Dragomir D, Mahadevan S, Wright J, Alvarado-Montes JA, Bender C, Blake CH, Caldwell D, Cañas CI, Cochran WD, Dalba P, Everett ME, Fernandez P, Golub E, Guillet B, Halverson S, Hebb L, Higuera J, Huang CX, Klusmeyer J, Knight R, Leroux L, Logsdon SE, Loose M, McElwain MW, Monson A, Ninan JP, Nowak G, Palle E, Patel Y, Pepper J, Primm M, Rajagopal J, Robertson P, Roy A, Schneider DP, Schwab C, Schweiker H, Sgro L, Shimizu M, Simard G, Stefánsson G, Stevens DJ, Villanueva S, Wisniewski J, Will S, Ziegler C.   +59 more
europepmc   +1 more source

Purpose‐Adaptable Reinforced 3D Hyaluronic‐Acid Based Platform to Study Pathomechanisms of the Central Nervous System

Advanced Healthcare Materials, EarlyView.
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu, Esra Tuerker, Anna‐Lena Wiessler, Jessica Faber, Ievgenii Liashenko, Jeanette Weigelt, Jörg Tessmar, Paul D. Dalton, Sibylle Jablonka, Mateo S. Andrade Mier, Carmen Villmann, Silvia Budday, Natascha Schaefer   +12 more
wiley   +1 more source

Planets larger than Neptune have elevated eccentricities. [PDF]

Proc Natl Acad Sci U S A
Gilbert GJ, Petigura EA, Entrican PM.
europepmc   +1 more source

Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia

Advanced Healthcare Materials, EarlyView.
This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi, Tanveer Ul Islam, Oscar M.J.A. Stassen, Naomie Amsing, Jan de Boer, Jaap M.J. den Toonder   +5 more
wiley   +1 more source

Helioseismic inference of the solar radiative opacity. [PDF]

Nat Commun
Buldgen G, Pain JC, Cossé P, Blancard C, Gilleron F, Pradhan AK, Fontes CJ, Colgan J, Noels A, Christensen-Dalsgaard J, Deal M, Ayukov SV, Baturin VA, Oreshina AV, Scuflaire R, Pinçon C, Lebreton Y, Corbard T, Eggenberger P, Salmon S, Hakel P, Kilcrease DP.   +21 more
europepmc   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

A hot white dwarf merger remnant revealed by an ultraviolet detection of carbon. [PDF]

Nat Astron
Sahu S, Bédard A, Gänsicke BT, Tremblay PE, Koester D, Farihi J, Hermes JJ, Hollands MA, Cunningham T, Redfield S.   +9 more
europepmc   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Evidence for Dark Energy Driven by Star Formation: Information Dark Energy? [PDF]

Entropy (Basel)
Gough MP.
europepmc   +1 more source