Results 91 to 100 of about 174,695 (330)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Stellar Ages: A Code to Infer Properties of Stellar Populations

The Astrophysical Journal
We present a novel statistical algorithm, Stellar Ages, which currently infers the age, metallicity, and extinction posterior distributions of stellar populations from their magnitudes.
Joseph J. Guzman, Jeremiah W. Murphy, Andrés F. Barrientos, Benjamin F. Williams, Julianne J. Dalcanton   +4 more
doaj   +1 more source

Chemical Yields from the First Stars

, 1999
We examine the dependence of stellar yields on the metallicity Z of the stellar population. This effect may be important for the very first chemical enrichment from Population III stars, at very low Z.
Portinari, L.
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

A Blueprint for the Milky Way’s Stellar Populations. II. Improved Isochrone Calibration in the SDSS and Pan-STARRS Photometric Systems [PDF]

, 2021
Deokkeun An, Timothy C. Beers, Deokkeun An, Timothy C. Beers   +3 more
openalex   +1 more source

The Stellar Populations of the M31 Halo Substructure

The Astrophysical Journal, 2005
5 pages, 3 figurs, ApJL ...
Ferguson, AMN, Johnson, RA, Faria, DC, Irwin, MJ, Ibata, RA, Johnston, KV, Lewis, GF, Tanvir, NR   +7 more
openaire   +4 more sources

The MASSIVE Survey II: Stellar Population Trends Out to Large Radius in Massive Early Type Galaxies

, 2015
We examine stellar population gradients in ~100 massive early type galaxies spanning 180 < sigma* < 370 km/s and M_K of -22.5 to -26.5 mag, observed as part of the MASSIVE survey (Ma et al. 2014).
Blakeslee, John P., Greene, Jenny E., Janish, Ryan, Ma, Chung-Pei, McConnell, Nicholas J., Murphy, Jeremy D., Thomas, Jens   +6 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Detection of a Spatially Extended Stellar Population in M33: A Shallow Stellar Halo?

The Astrophysical Journal
We analyze the outer regions of M33, beyond 15 kpc in projected distance from its center, using Subaru/Hyper Suprime-Cam multicolor imaging. We identify red giant branch (RGB) stars and red clump (RC) stars using the surface-gravity-sensitive NB515 ...
Itsuki Ogami, Yutaka Komiyama, Masashi Chiba, Mikito Tanaka, Puragra Guhathakurta, Evan N. Kirby, Rosemary F. G. Wyse, Carrie Filion, Takanobu Kirihara, Miho N. Ishigaki, Kohei Hayashi   +10 more
doaj   +1 more source