Results 101 to 110 of about 165,855 (235)

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

A Study of Primordial Very Massive Star Evolution. II. Stellar Rotation and Gamma-Ray Burst Progenitors

open access: yesThe Astrophysical Journal
We calculate new evolutionary models of rotating primordial very massive stars, with initial mass from 100 M _⊙ to 200 M _⊙ , for two values of the initial metallicity Z = 0 and Z = 0.0002.
Guglielmo Volpato   +6 more
doaj   +1 more source

Stellar population in star formation regions of galaxies

open access: yesOpen Astronomy, 2018
We developed techniques for searching young unresolved star groupings (clusters, associations, and their complexes) and of estimating their physical parameters.
Gusev Alexander S.   +5 more
doaj   +1 more source

Calibrated stellar models for metal-poor population

open access: yes, 2004
We extend to lower metallicities recent evolutionary computations devoted to Magellanic Clouds stars, presenting and discussing new stellar models with Z=0.0002, 0.0004, 0.0006, 0.001 and suitable assumptions about the original He content.
Alexander   +85 more
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Sloan Digital Sky Survey IV MaStar: Quantification and Abatement of Interstellar Absorption in the Largest Empirical Stellar Spectral Library

open access: yesThe Astrophysical Journal
We assess the impact of Ca ii λ λ 3934, 3969 and Na i λ λ 5891, 5897 absorption arising in the interstellar medium (ISM) on the Sloan Digital Sky Survey-IV MaNGA Stellar Library (MaStar) and produce corrected spectroscopy for 80% of the 24,162-star ...
Kate H. R. Rubin   +8 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Far-ultraviolet to Far-infrared Spectral Energy Distribution Modeling of the Star Formation History across M31

open access: yesThe Astronomical Journal
Our neighboring galaxy M31 has been recently surveyed at the far- and near-ultraviolet (FUV and NUV) with the UVIT telescope on AstroSat, which provides unprecedented sensitivity to young stellar populations.
Denis A. Leahy   +2 more
doaj   +1 more source

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