Results 131 to 140 of about 174,695 (330)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Shooting for the Stars: Jet-mode Feedback and AGN Jet Deceleration from Stellar Mass Loading

open access: yesThe Astrophysical Journal
Active Galactic Nucleus (AGN) jets are thought to be vital ingredients in galaxy evolution through the action of kinetic feedback; however, how narrow, relativistic outflows couple to galaxies remains an open question.
Talia M. O’Shea   +4 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Concealing Circumbinary Planets with Tidal Shrinkage

open access: yesThe Astrophysical Journal
Of the 14 transiting planets that have been detected orbiting eclipsing binaries (“circumbinary planets”), none have been detected with stellar binary orbital periods shorter than 7 days, despite such binaries existing in abundance.
Saahit Mogan, J.J. Zanazzi
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Sloan Digital Sky Survey IV MaStar: Quantification and Abatement of Interstellar Absorption in the Largest Empirical Stellar Spectral Library

open access: yesThe Astrophysical Journal
We assess the impact of Ca ii λ λ 3934, 3969 and Na i λ λ 5891, 5897 absorption arising in the interstellar medium (ISM) on the Sloan Digital Sky Survey-IV MaNGA Stellar Library (MaStar) and produce corrected spectroscopy for 80% of the 24,162-star ...
Kate H. R. Rubin   +8 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Far-ultraviolet to Far-infrared Spectral Energy Distribution Modeling of the Star Formation History across M31

open access: yesThe Astronomical Journal
Our neighboring galaxy M31 has been recently surveyed at the far- and near-ultraviolet (FUV and NUV) with the UVIT telescope on AstroSat, which provides unprecedented sensitivity to young stellar populations.
Denis A. Leahy   +2 more
doaj   +1 more source

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