Results 61 to 70 of about 165,855 (235)

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The Mass of the Vela Pulsar Progenitor and the Age of the Vela-Puppis Complex

The Astrophysical Journal
The association of the Vela Pulsar with the Vela Supernova Remnant has long supported the hypothesis that core-collapse supernovae yield neutron stars, but its surrounding stellar population now offers new insights into progenitor evolution.
Jeremiah W. Murphy, Andrés F. Barrientos, René Andrae, Joseph Guzman, Benjamin F. Williams, Julianne J. Dalcanton, Brad Koplitz   +6 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Imprints of galaxy evolution on H ii regions Memory of the past uncovered by the CALIFA survey

, 2014
H ii regions in galaxies are the sites of star formation and thus particular places to understand the build-up of stellar mass in the universe. The line ratios of this ionized gas are frequently used to characterize the ionization conditions.
Bekeraite, S., Bland-Hawthorn, J., Bomans, D., collaboration, The CALIFA, de Lorenzo-Cáceres, A., Delgado, R. González, Díaz, A., Ellis, S., Galbany, L., García-Benito, R., Iglesias-Páramo, J., Kehrig, C., Lopez-Sanchez, A. R., Marino, R. A., Mast, D., Mendez-Abreu, J., Mendoza, M. A., Miralles-Caballero, D., Mollá, M., Monreal-Ibero, A., Papaderos, P., Pasquali, A., Perez, E., Rosales-Ortega, F. F., Roth, M. M., Sanchez, S. F., Sánchez-Menguiano, L., van de Ven, G., Wisotzki, L., Ziegler, B.   +29 more
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Stellar populations of classical and pseudo-bulges for a sample of isolated spiral galaxies

, 2011
In this paper we present the stellar population synthesis results for a sample of 75 bulges in isolated spiral Sb-Sc galaxies, using the spectroscopic data from the Sloan Digital Sky Survey and the STARLIGHT code.
A. Durbala, A. Mateus, A. Pizzella, A.W. Graham, A.W. Graham, C.A. Tremonti, D.A. Gadotti, D.A. Gadotti, D.B. Fisher, D.B. Fisher, D.B. Fisher, D.J. Schlegel, E.E. Salpeter, F. Barbera La, G. Bruzual, G. Kauffmann, J. Gorgas, J. Kormendy, J. Kormendy, J. Kormendy, J.-F. Borgne Le, J.A. Cardelli, J.K. Adelman-McCarthy, K.N. Abazajian, L. Morelli, L. Verdes-Montenegro, L.A. MacArthur, N.V. Asari, P. Jablonka, Ph. Héraudeau, Ph. Prugniel, R. Bender, R. Bender, R. Cid Fernandes, R. Cid Fernandes, R.B. Larson, S.M. Faber, V.E. Karachentseva, Yinghe Zhao   +38 more
core   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Starspots and Undetected Binary Stars Have Distinct Signatures in Young Stellar Associations

The Astrophysical Journal
Young stars form in associations, meaning that young stellar associations provide an ideal environment to measure the age of a nominally coeval population.
Kendall Sullivan, Adam L. Kraus
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

A Census of Star Formation Histories of Massive Galaxies at 0.6 < z < 1 from Spectrophotometric Modeling Using Bagpipes and Prospector

The Astrophysical Journal
We present individual star formation histories (SFHs) of ∼3000 massive galaxies (log( M _* / M _⊙ ) > 10.5) from the Large Early Galaxy Astrophysics Census spectroscopic survey at a lookback time of ∼7 billion yr and quantify the population trends ...
Yasha Kaushal, Angelos Nersesian, Rachel Bezanson, Arjen van der Wel, Joel Leja, Adam Carnall, Anna Gallazzi, Stefano Zibetti, Gourav Khullar, Marijn Franx, Adam Muzzin, Anna de Graaff, Camilla Pacifici, Katherine E. Whitaker, Eric F. Bell, Marco Martorano   +15 more
doaj   +1 more source