Results 81 to 90 of about 174,695 (330)

RCW36: characterizing the outcome of massive star formation [PDF]

, 2013
Massive stars play a dominant role in the process of clustered star formation, with their feedback into the molecular cloud through ionizing radiation, stellar winds and outflows.
Balog, Z., Bik, A., Ellerbroek, L. E., Kaper, L., Maaskant, K. M., Paalvast, M., Sana, H., Tramper, F., Waters, L. B. F. M.   +8 more
core   +5 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Stellar evolution and stellar populations

, 2019
I will overview how the theory of stellar evolution and stellar populations evolved to explain the rich features observed in large surveys of the Magellanic Clouds -- going from subtle features in colour-magnitude diagrams to striking sequences in period-magnitude diagrams.
openaire   +1 more source

Imprints of galaxy evolution on H ii regions Memory of the past uncovered by the CALIFA survey

, 2014
H ii regions in galaxies are the sites of star formation and thus particular places to understand the build-up of stellar mass in the universe. The line ratios of this ionized gas are frequently used to characterize the ionization conditions.
Bekeraite, S., Bland-Hawthorn, J., Bomans, D., collaboration, The CALIFA, de Lorenzo-Cáceres, A., Delgado, R. González, Díaz, A., Ellis, S., Galbany, L., García-Benito, R., Iglesias-Páramo, J., Kehrig, C., Lopez-Sanchez, A. R., Marino, R. A., Mast, D., Mendez-Abreu, J., Mendoza, M. A., Miralles-Caballero, D., Mollá, M., Monreal-Ibero, A., Papaderos, P., Pasquali, A., Perez, E., Rosales-Ortega, F. F., Roth, M. M., Sanchez, S. F., Sánchez-Menguiano, L., van de Ven, G., Wisotzki, L., Ziegler, B.   +29 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Starspots and Undetected Binary Stars Have Distinct Signatures in Young Stellar Associations

The Astrophysical Journal
Young stars form in associations, meaning that young stellar associations provide an ideal environment to measure the age of a nominally coeval population.
Kendall Sullivan, Adam L. Kraus
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Metal-poor Stars in the MW Disk: Resonant Cooling of Vertical Oscillations of Halo Stars in Barred Galaxies

The Astrophysical Journal Letters
Using numerical simulations of a barred disk galaxy embedded in nonspinning and spinning dark matter (DM) halos, we present a novel mechanism of “cooling” the vertical oscillations of DM particles, which acquire disk kinematics.
Xingchen Li, Isaac Shlosman, Daniel Pfenniger, Clayton Heller   +3 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

A Census of Star Formation Histories of Massive Galaxies at 0.6 < z < 1 from Spectrophotometric Modeling Using Bagpipes and Prospector

The Astrophysical Journal
We present individual star formation histories (SFHs) of ∼3000 massive galaxies (log( M _* / M _⊙ ) > 10.5) from the Large Early Galaxy Astrophysics Census spectroscopic survey at a lookback time of ∼7 billion yr and quantify the population trends ...
Yasha Kaushal, Angelos Nersesian, Rachel Bezanson, Arjen van der Wel, Joel Leja, Adam Carnall, Anna Gallazzi, Stefano Zibetti, Gourav Khullar, Marijn Franx, Adam Muzzin, Anna de Graaff, Camilla Pacifici, Katherine E. Whitaker, Eric F. Bell, Marco Martorano   +15 more
doaj   +1 more source