The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Spectropolarimetry for Discerning Geometry and Structure in Circumstellar Media of Hot Massive Stars
GalaxiesSpectropolarimetric techniques are a mainstay of astrophysical inquiry, ranging from Solar System objects to the Cosmic Background Radiation. This review highlights applications of stellar polarimetry for massive hot stars, particularly in the context of
Richard Ignace +5 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
New Stellar Parameters, Metallicities, and Elemental Abundance Ratios for 311 Metal-poor Stars
The Astronomical JournalWe present equivalent widths, improved model atmosphere parameters, and revised abundances for 14 species of 11 elements derived from high-resolution optical spectroscopy of 311 metal-poor stars.
Sanil Mittal, Ian U. Roederer
doaj +1 more source
The evolution of the V − K colours of single stellar populations [PDF]
, 1998 Léo Girardi, Gianpaolo Bertelli
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Stellar Mass Segregation in Dark Matter Halos
The Astrophysical JournalWe study the effect of stellar mass segregation driven by collisional relaxation within the potential well of a smooth dark matter halo. This effect is of particular relevance for old stellar systems with short crossing times, where small collisional ...
Raphaël Errani +2 more
doaj +1 more source
A stellar census in globular clusters with MUSE: multiple populations chemistry in NGC 2808 [PDF]
, 2019 M. Latour +10 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source