Results 81 to 90 of about 152,062 (293)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Intrinsic Flattening of Galaxy Disks

The Astrophysical Journal
Highly inclined (edge-on) disk galaxies offer the unique perspective to constrain their intrinsic flattening, c / a , where c and a are, respectively, the vertical and long radial axes of the disk measured at suitable stellar densities.
Jeremy Favaro, Stéphane Courteau, Sébastien Comerón, Connor Stone   +3 more
doaj   +1 more source

Stellar flares observed in long cadence data from the Kepler mission

, 2017
We aim to perform a statistical study of stellar flares observed by Kepler. We want to study the flare amplitude, duration, energy and occurrence rates, and how they are related to the spectral type and rotation period.
Debosscher, Jonas, Shariati, Hoda, Van Doorsselaere, Tom   +2 more
core   +1 more source

Type Ia supernovae as stellar endpoints and cosmological tools [PDF]

Nature Communications, 2011
Empirically, Type Ia supernovae are the most useful, precise, and mature tools for determining astronomical distances. Acting as calibrated candles they revealed the presence of dark energy and are being used to measure its properties. However, the nature of the SN Ia explosion, and the progenitors involved, have remained elusive, even after seven ...
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Grand Design versus Multiarmed Spiral Galaxies: Dependence on Galaxy Structure

The Astronomical Journal
We developed an algorithm to use Galaxy Zoo 3D spiral arm masks produced by citizen scientist volunteers to semiautomatically classify spiral galaxies as either multiarmed or grand design spirals. Our final sample consists of 299 multiarmed and 245 grand
Beverly J. Smith, Matthew Watson, Mark L. Giroux, Curtis Struck   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Accurate and Robust Stellar Rotation Periods Catalog for 82771 Kepler Stars Using Deep Learning

The Astronomical Journal
We propose a new framework to predict stellar properties from light curves. We analyze the light-curve data from the Kepler space mission and develop a novel tool for deriving the stellar rotation periods for main-sequence stars.
Ilay Kamai, Hagai B. Perets
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source