Results 51 to 60 of about 92,514 (295)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
A Radio-loud Semiregular Variable
The Astrophysical JournalAs a byproduct of our search for Galactic stellar systems with gamma-ray emission, we have identified an unrelated cool and evolved star (IRC-10412) that attracted our attention due to its strong radio emission level with a spectral index matching ...
Pedro L. Luque-Escamilla, Josep Martí
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Spectroscopy of the Stellar Wind in the Cygnus X-1 System
Acta Polytechnica, 2011 The X-ray luminosity of black holes is produced through the accretion of material from their companion stars. Depending on the mass of the donor star, accretion of the material falling onto the black hole through the inner Lagrange point of the system or
I. Miškovičová +5 more
doaj
Critical Metallicity of Cool Supergiant Formation. I. Effects on Stellar-mass Loss and Feedback
The Astrophysical Journal, 2023 This paper systematically studies the relation between metallicity and mass loss of massive stars. We perform one-dimensional stellar evolution simulations and build a grid of ∼2000 models with initial masses ranging between 11 and 60 M _⊙ and absolute ...
Po-Sheng Ou +3 more
doaj +1 more source
, 2012 The true mass-loss rates from massive stars are important for many branches of astrophysics. For the correct modeling of the resonance lines, which are among the key diagnostics of stellar mass-loss, the stellar wind clumping turned out to be very ...
A. Feldmeier +57 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Rotational Evolution of Classical T Tauri Stars: Models and Observations
The Astrophysical JournalWe developed a grid of stellar rotation models for low-mass and solar-type classical T Tauri stars (CTTS; 0.3 M _⊙ < M _* < 1.2 M _⊙ ). These models incorporate the star–disk interaction and magnetospheric ejections to investigate the evolution of the ...
Javier Serna +19 more
doaj +1 more source
Spektra: Jurnal Fisika dan AplikasinyaMassive stars (over 8 solar masses) undergo intricate cosmic journeys. Their evolution, shaped by parameters like stellar wind, rotation velocity, and overshoot, generally includes the pre-main sequence, main sequence, and post-main sequence phases.
Alin Hafizhah Adira, Aprilia
doaj +1 more source