Results 71 to 80 of about 91,502 (296)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
The applicability of the wind compression model
, 2014 Compression of the stellar winds from rapidly rotating hot stars is described by the wind compression model. However, it was also shown that rapid rotation leads to rotational distortion of the stellar surface, resulting in the appearance of non-radial ...
Cariková, Zuzana, Skopal, Augustin
core +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
On the interaction of jets with stellar winds in XRBs
, 2010 We present the first three-dimensional simulations of the evolution of a microquasar jet inside the binary-star system. The aim is to study the interaction of these jets with the stellar wind from a massive companion and the possible locations of high ...
Bosch-Ramon, V. +2 more
core +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
The Astrophysical JournalWe present an analysis of the effects of spectral resolution and aperture scale on derived galaxy properties using far-ultraviolet (FUV) spectra of local star-forming galaxies from the International Ultraviolet Explorer ( R ∼ 250, field of view (FOV ...
Ilyse Clark +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Stellar Wind Accretion in GX301-2: Evidence for a High-density Stream
, 2007 The X-ray binary system GX301-2 consists of a neutron star in an eccentric orbit accreting from the massive early-type star WRAY 977. It has previously been shown that the X-ray orbital light curve is consistent with existence of a gas stream flowing out
Castor +21 more
core +1 more source
The sculpting of rectangular and jet-like morphologies in supernova remnants by anisotropic equatorially confined progenitor stellar winds [PDF]
, 2023 P. F. Velázquez +7 more
openalex +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source