Results 261 to 270 of about 1,100,727 (344)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Binary progenitor systems for Type Ic supernovae. [PDF]

Nat Commun
Solar M, Michałowski MJ, Nadolny J, Galbany L, Hjorth J, Zapartas E, Sollerman J, Hunt L, Klose S, Koprowski M, Leśniewska A, Małkowski M, Nicuesa Guelbenzu AM, Ryzhov O, Savaglio S, Schady P, Schulze S, de Ugarte Postigo A, Vergani SD, Watson D, Wróblewski R.   +20 more
europepmc   +1 more source

X‐Ray Spectral Study of the Photoionized Stellar Wind in Vela X‐1 [PDF]

, 2006
Shin Watanabe, M. Šako, M. Ishida, Yoshitaka Ishisaki, S. M. Kahn, Takayoshi Kohmura, F. Nagase, F. Paerels, Tadayuki Takahashi   +8 more
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

The spectral evolution of white dwarfs: where do we stand? [PDF]

Astrophys Space Sci
Bédard A.
europepmc   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

From gas to ice giants: A unified mechanism for equatorial jets. [PDF]

Sci Adv
Duer-Milner K, Gavriel N, Galanti E, Tziperman E, Kaspi Y.   +4 more
europepmc   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Neutron capture measurements for s-process nucleosynthesis: A review about CERN n_TOF developments and contributions. [PDF]

Eur Phys J A Hadron Nucl
Domingo-Pardo C, Aberle O, Alcayne V, Alpar G, Halabi MA, Amaducci S, Babiano V, Bacak M, Balibrea-Correa J, Bartolomé J, Bernardes AP, Gameiro BB, Berthoumieux E, Beyer R, Birch M, Boromiza M, Bosnar D, Brusasco B, Caamaño M, Cahuzac A, Calviño F, Calviani M, Cano-Ott D, Casanovas A, Castelluccio DM, Catlett D, Cerutti F, Cescutti G, Chiaveri E, Claps G, Colombetti P, Colonna N, Camprini PC, Cortés G, Cortés-Giraldo MA, Cosentino L, Cristallo S, D'Ottavi A, de la Fuente Rosales G, Dellmann SF, Diakaki M, Di Castro M, Di Chicco A, Dietz M, Dupont E, Durán I, Eleme Z, Eslami M, Fargier S, Fernández-Domínguez B, Finocchiaro P, Flanagan W, Furman V, Gandhi A, García-Infantes F, Gawlik-Ramiega A, Gervino G, Gilardoni S, González-Romero E, Goula S, Griesmayer E, Guerrero C, Gunsing F, Gustavino C, Heyse J, Hillman W, Jenkins DG, Jericha E, Junghans A, Kadi Y, Kaperoni K, Kelly I, Kokkoris M, Kopatch Y, Krtička M, Kyritsis N, Lederer-Woods C, Lerendegui-Marco J, Manna A, Martínez T, Martínez-Cañada M, Masi A, Massimi C, Mastinu P, Mastromarco M, Maugeri EA, Mazzone A, Mendoza E, Mengoni A, Michalopoulou V, Milazzo PM, Moldenhauer J, Mucciola R, González EM, Musumarra A, Negret A, Odusina E, Papanikolaou D, Patronis N, Pavón-Rodríguez JA, Pellegriti MG, Pérez-Maroto P, de Rada Fiol AP, Perfetto G, Perkowski J, Petrone C, Pieretti N, Piersanti L, Pirovano E, Porras I, Praena J, Quesada JM, Reifarth R, Rochman D, Romanets Y, Rooney A, Rovira G, Rubbia C, Sánchez-Caballero A, Sahoo RN, Scarpa D, Schillebeeckx P, Smith AG, Sosnin NV, Spelta M, Stamati ME, Stasiak K, Tagliente G, Tarifeño-Saldivia A, Tarrío D, Torres-Sánchez P, Tosi S, Tsiledakis G, Valenta S, Vaz P, Vecchio G, Vescovi D, Vlachoudis V, Vlastou R, Wallner A, Weiss C, Woods PJ, Wright T, Wu R, Žugec P, The n_TOF Collaboration.   +145 more
europepmc   +1 more source