Results 141 to 150 of about 1,081,551 (253)

Smoking Abstinence Elicits Hyperalgesia: Neural Mechanism, Clinical Implications, and Pharmacological Managements

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
The cycle between nicotine use and pain modulation. Cigarette smoking leads to nicotine entering the body, which binds to nicotinic acetylcholine receptors (nAChRs) in the brain, triggering the release of different neurotransmitters, including dopamine (DA), norepinephrine (NE), serotonin (5‐HT), and GABA.
Shan‐shan Hu   +3 more
wiley   +1 more source

P7C3 Compounds as Targeted Mitochondrial Therapeutics for Brain Disorders

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
P7C3 activates NAMPT, the rate‐limiting enzyme in the NAD+ salvage pathway, elevating NAD+ levels in neurons. This engages SIRT1‐dependent nuclear signaling and SIRT3‐dependent mitochondrial regulation, enhancing mitochondrial quality control, reducing oxidative stress, and promoting neuronal survival.
Yajing Chen   +7 more
wiley   +1 more source

Cancer‐related pain: A bidirectional modulator of cancer progression

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He   +5 more
wiley   +1 more source

Cascade‐targeted intervention of the NLRP3 inflammasome and downstream angiogenesis by curcumin nanoparticles for ocular neovascularization therapy

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Ultrasound‐microreactor synthesizes monodisperse 125 nm Cur‐NPs with enhanced solubility. Cur‐NPs suppress VEGF signaling and retinal neovascularization via the NLRP3 axis. Multi‐omics profiling reveals that Cur‐NPs reprogram retinal microglia and metabolic pathways.
Siyu Jiang   +9 more
wiley   +1 more source

Ultrasound-guided Stellate Ganglion Block As Rescue Therapy For Refractory Ventricular Tachycardia - A Case Report

open access: yes
Refractory ventricular arrhythmia or electrical storm is a dangerous cardiac condition that entails three or more episodes of ventricular arrhythmia that are resistant to treatment within 24 hours.
Yalun, Jeff
core   +1 more source

Nodular Fasciitis of the Parotid Gland Mimicking Pleomorphic Adenoma: Cytological Features of a Diagnostic Pitfall

open access: yesDiagnostic Cytopathology, Volume 54, Issue 9, Page E221-E226, September 2026.
ABSTRACT Nodular fasciitis (NF) is a self‐limiting mesenchymal neoplasm that typically occurs in the subcutaneous tissue of the extremities, trunk, and head and neck region; involvement of the parotid gland is very rare. The cytological features of NF can closely mimic those seen in salivary gland neoplasms, particularly pleomorphic adenoma (PA ...
Xiaobing Jin   +4 more
wiley   +1 more source

Does acute response to stellate ganglion block predict the success of cardiac sympathetic denervation? Preliminary evidence. [PDF]

open access: yesHeart Rhythm O2
Doundoulakis I   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy