Results 131 to 140 of about 269,242 (268)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

DP042 | IMPACT OF ANTIFUNGAL PROPHYLAXIS ON TRANSPLANT-RELATED MORTALITY IN MISMATCHED ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT): A PROSPECTIVE EXPERIENCE FROM A SINGLE TRANSPLANT PROGRAM

open access: yesHaematologica
Background In the allogeneic HSCT, the incidence of Invasive Fungal Disease is 7-9% with high rate of mortality. Although the antifungal prophylaxis is crucial, the role of anidulafungin is unknown.
A. Carobene   +19 more
doaj  

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

Erratum to: “Lower incidence of chronic graft-versus-host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft-versus-host disease following allogeneic stem cell transplantation”

open access: yesHaematologica
Iryna Lastovytska   +14 more
doaj   +1 more source

P653: CML LONG-TERM LEUKEMIC STEM CELL PERSISTENCE IS INFLUENCED BY MYELOFIBROSIS AT DIAGNOSIS

open access: yesHemaSphere, 2023
Henrike Jacobi   +11 more
doaj   +1 more source

Unraveling the Role of Zonulin in Allogeneic Hematopoietic Stem Cell Transplantation: A Multicenter Study. [PDF]

open access: yesInt J Mol Sci
Soares Ferreira Junior A   +12 more
europepmc   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

open access: yesAdvanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang   +10 more
wiley   +1 more source

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