Results 31 to 40 of about 1,446,025 (307)

Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant. [PDF]

, 2017
The advent of large-scale in vitro differentiation of human stem cell-derived insulin-producing cells (SCIPC) has brought us closer to treating diabetes using stem cell technology. However, decades of experiences from islet transplantation show that
Faleo, Gaetano, Freise, Jonathan E, Hebrok, Matthias, Nair, Gopika G, Nguyen, Vinh, Parent, Audrey V, Russ, Holger A, Szot, Gregory L, Tang, Qizhi, Villanueva, Karina E, Wisel, Steven   +10 more
core   +6 more sources

Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors

Bone Marrow Transplantation, 2019
Information on incidence, and factors associated with mortality is a prerequisite to improve outcome after hematopoietic stem cell transplantation (HSCT).
J. Styczyński, G. Tridello, L. Koster, S. Iacobelli, A. van Biezen, S. van der Werf, M. Mikulska, L. Gil, C. Cordonnier, P. Ljungman, D. Averbuch, S. Cesaro, R. de la Cámara, H. Baldomero, P. Bader, G. Basak, C. Bonini, R. Duarte, C. Dufour, J. Kuball, A. Lankester, S. Montoto, A. Nagler, J. Snowden, N. Kröger, M. Mohty, A. Gratwohl   +26 more
semanticscholar   +1 more source

One novel ACOT7–NPHP4 fusion gene identified in one patient with acute lymphoblastic leukemia: a case report

BMC Medical Genomics, 2022
Background Acute lymphoblastic leukemia (ALL) is a type of heterogeneous hematopoietic malignancy that accounts for approximately 20% of adult ALL. Although ALL complete remission (CR) rate has increased to 85–90% after induction chemotherapy, 40–50% of ...
Xin Zong, Zhijie Kang, Dan Huang, Xuehong Zhang, Yuan Gao, Haina Wang, Weiling Li, Jinsong Yan   +7 more
doaj   +1 more source

MLL-SEPT5 Fusion Transcript in Myelodysplastic Syndrome Patient With t(11;22)(q23;q11)

Frontiers in Medicine, 2021
Objectives: This study aimed to identify unknown mixed lineage leukemia (MLL) translocation partner genes in a de novo patient with myelodysplastic syndrome (MDS) with t(11;22)(q23;q11) and investigate the clinical and molecular features of this patient ...
Duobing Zou, Ying Chen, Ningning Wu, Yi Zhang, Guifang Ouyang, Qitian Mu   +5 more
doaj   +1 more source

Potential for Stem Cells Therapy in Alzheimer’s Disease: Do Neurotrophic Factors Play Critical Role? [PDF]

, 2017
Alzheimer’s disease (AD) is one of the most common causes of dementia. Despite several decades of research in AD, there is no standard disease- modifying therapy available and currentlyapproved drugs provide only symptomatic relief.
Anand, Akshay, Bali, Parul, Banik, Avijit, Lahiri, Debomoy K., Nehru, Bimla   +4 more
core   +2 more sources

The genomic analysis brings a new piece to the molecular jigsaw of idiopathic erythrocytosis

Experimental Hematology & Oncology, 2022
Erythrocytosis is a clinical condition characterized by increased red cell mass, hemoglobin, and hematocrit values. A significant fraction of patients is described as having idiopathic erythrocytosis.
Antonella Zagaria, Francesco Tarantini, Paola Orsini, Luisa Anelli, Cosimo Cumbo, Nicoletta Coccaro, Giuseppina Tota, Crescenzio Francesco Minervini, Elisa Parciante, Maria Rosa Conserva, Immacolata Redavid, Alessandra Ricco, Immacolata Attolico, Giorgina Specchia, Pellegrino Musto, Francesco Albano   +15 more
doaj   +1 more source

Current status of autologous stem cell transplantation for multiple myeloma

Blood Cancer Journal, 2019
More than 30 years after its introduction, autologous stem cell transplantation (ASCT) remains the standard of care for young patients with newly diagnosed multiple myeloma. Not only did the arrival of novel agents such as immunomodulatory drugs (IMiDs),
Rama Al Hamed, A. Bazarbachi, F. Malard, J. Harousseau, M. Mohty   +4 more
semanticscholar   +1 more source

Effector Functions of Natural Killer Cell Subsets in the Control of Hematological Malignancies. [PDF]

, 2015
Treatment of hematological malignant disorders has been improved over the last years, but high relapse rate mainly attributable to the presence of minimal residual disease still persists.
Biassoni, Biron, Björklund, Brodin, Bryceson, Burns, Campbell, Cooley, Cooper, Cooper, Curti, Davies, Di Santo, Di Santo, Farag, Fehniger, Fogler, Foley, Freud, Gasser, Gilfillan, Grimm, Guethlein, Herberman, Huntington, Joncker, Kiessling, Killig, King, Kröger, Lajoie, Lanier, Leong, Ljunggren, Lowe, Lundqvist, Mancusi, McQueen, Miller, Moretta, Moretta, Moretta, Nguyen, Oevermann, Ouyang, Perussia, Phillips, Romagnani, Romee, Rosenberg, Rosenberg, Rosenberg, Ruggeri, Santoni, Stabile, Stabile, Stern, Stringaris, Thielens, Torelli, Trinchieri, Trinchieri, Vago, Valés-Gómez, Venstrom, Vivier, Whitelaw, Zorn   +67 more
core   +1 more source

Cholangiocytes: Cell transplantation [PDF]

, 2017
Background:Due to significant limitations to the access to orthotropic liver transplantation, cell therapies forliver diseases have gained large interest worldwide.Scope of review:To revise current literature dealing with cell therapy for liver diseases.
Alvaro, Domenico, Bragazzi, MARIA CONSIGLIA, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, Ridola, Lorenzo   +5 more
core   +1 more source

FLT3-ITD Compared with DNMT3A R882 Mutation Is a More Powerful Independent Inferior Prognostic Factor in Adult Acute Myeloid Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Cohort Study

Turkish Journal of Hematology, 2018
Objective: This study aimed to evaluate DNMT3A exon 23 mutations and their prognostic impacts in the presence of NPM1 and FLT3 mutations in acute myeloid leukemia (AML) patients who underwent allogeneic hematopoietic stem cell transplantation (HSCT ...
Majid Teremmahi Ardestani, Ahmad Kazemi, Bahram Chahardouli, Saeed Mohammadi, Mohsen Nikbakht, Shahrbano Rostami, Mahdi Jalili, Mohammad Vaezi, Kamran Alimoghaddam, Ardeshir Ghavamzadeh   +9 more
doaj   +1 more source