Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
RESEARCH OF TRENDS IN DEMAND FOR STEM SKILLS IN THE ECONOMIC SECTOR
Formulation of the problem. In today's economy, STEM skills (Science, Technology, Engineering, Mathematics) are becoming essential for data analysis, market modeling, and decision-making.
Wen Zhang
doaj +1 more source
H-1Bs: How Do They Stack Up to US Born Workers? [PDF]
Combining unique individual level H-1B data from U.S. Citizenship and Immigration Services (USCIS) and data from the 2009 American Community Survey, we analyze earnings differences between H-1B visa holders and US born workers in STEM occupations.
Hayes, Joseph, Lofstrom, Magnus
core
Barriers to Pursuing STEM-Related Careers: Perceptions of Hispanic Girls Enrolled in Advanced High School STEM Courses [PDF]
Researchers indicate that the United States has fallen behind other nations in science, technology, engineering, and mathematics (STEM) education (President\u27s Council of Advisors on Science and Technology, 2010, 2012).
Bustamante, Rebecca M. +2 more
core +1 more source
Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen +11 more
wiley +1 more source
STEM education and outcomes in Vietnam: Views from the social gap and gender issues [PDF]
United Nations’ Sustainable Development Goals 4 Quality Education has highlighted major challenges for all nations to ensure inclusive and equitable quality access to education, facilities for children, and young adults.
Cuong, Nguyen Manh +7 more
core
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Introduction of STEAM education with the use of 3D technologies: modelling, scanning and printing [PDF]
Nothing in the world happens without innovations: new ideas, new products, and new solutions of the existing problems. Without science, technologies, engineering and STEM there will be no innovations.
Morze, Nataliia +5 more
core +2 more sources

