Results 61 to 70 of about 397,415 (261)
Agronomy, 2021 The present work evaluates the main adaptive mechanisms developed by young sweet cherry trees (Prunus avium L.) to cope with drought. For this purpose, the young trees were subjected to two drought cycles with different water stress intensities followed ...
Pedro José Blaya-Ros +3 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Sensors, 2016 Plant phenotyping is a very important topic in agriculture. In this context, data mining strategies may be applied to agricultural data retrieved with new non-invasive devices, with the aim of yielding useful, reliable and objective information.
Salvador Gutiérrez +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Plant Production Science, 2007 The Leaf Water Relations, Photosynthetic Parameters and Shoot Growth of Five Snap Bean Cultivars Were Assessed During The Drought Period To Determine Their Role In Alleviating Plant Water Deficit Imposed By Withholding Irrigation At Flowering. Soil Water
Hide Omae +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Phenotypic plasticity of stem water potential correlates with crop load in horticultural trees [PDF]
Tree Physiology, 2011 Conceptual models accounting for the influence of source:sink ratio on water relations of trees are theoretically relevant from a physiological perspective and practically important for irrigation scheduling. Midday stem water potential of horticultural trees often declines with increasing crop load but the actual response depends on environmental ...
Victor O, Sadras, Eduardo R, Trentacoste
openaire +2 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
HorticulturaeThe high number of grapevine (Vitis vinifera L.) cultivars grown world-wide are described and identified according to detailed morphological and morphometric descriptor lists.
Peter Lepej +8 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source