Results 151 to 160 of about 216,025 (255)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

The “stem” of chemoresistance [PDF]

Cell Cycle, 2010
Giulia, Bertolini, Laura, Gatti, Luca, Roz   +2 more
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Stems within a hill showing blackleg symptoms

, 1974
Several stems within a hill exhibiting blackleg symptoms. Rarely are all stems infected.Host/Plant: Potato (Solanum tuberosum subsp.
Claflin, Larry
core  

Improved extraction of phenolic compounds from fruits, leaves, and stems of Ugni candollei B. and Ugni molinae T. using pressurized aqueous glycerol

Data will be made available on request.This study explores the polyphenolic composition and antioxidant potential of fruits, leaves, and stems from two Chilean murta species: Ugni molinae Turcz (red murta) and Ugni candollei Barm (white murta). While the
Villalba, Marisol, Canales, Roberto I., Mariotti-Celis, María Salomé, Fuentes-Jorquera, Natalia, Pérez-Jiménez, Jara, Pérez-Correa, José Ricardo   +5 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Stem Cells [PDF]

Neuro-Oncology, 2010
L. Cheng, Z. Huang, W. Zhou, Q. Wu, J. Rich, S. Bao, P. Baxter, H. Mao, X. Zhao, Z. Liu, Y. Huang, H. Voicu, S. Gurusiddappa, J. M. Su, L. Perlaky, R. Dauser, H.-c. E. Leung, K. M. Muraszko, J. A. Heth, X. Fan, C. C. Lau, T.-K. Man, M. Chintagumpala, X.-N. Li, P. Clark, M. Zorniak, Y. Cho, X. Zhang, D. Walden, E. Shusta, J. Kuo, S. Sengupta, S. Goel-Bhattacharya, S. Kulkarni, B. Cochran, C. Cusulin, A. Luchman, S. Weiss, M. Wu, N. Fernandez, S. Agnihotri, R. Diaz, J. Rutka, M. Bredel, J. Karamchandani, S. Das, B. Day, B. Stringer, F. Al-Ejeh, M. Ting, J. Wilson, K. Ensbey, P. Jamieson, Z. Bruce, Y. C. Lim, C. Offenhauser, S. Charmsaz, L. Cooper, J. Ellacott, A. Harding, J. Lickliter, P. Inglis, B. Reynolds, D. Walker, M. Lackmann, A. Boyd, A. Berezovsky, L. Poisson, L. Hasselbach, S. Irtenkauf, A. Transou, T. Mikkelsen, A. C. deCarvalho, D. Emlet, C. Del Vecchio, P. Gupta, G. Li, S. Skirboll, A. Wong, J. Figueroa, T. Shahar, A. Hossain, F. Lang, S. Fouse, J. Nakamura, C. D. James, S. Chang, J. Costello, J. M. Frerich, S. Rahimpour, Z. Zhuang, J. D. Heiss, A. Golebiewska, D. Stieber, L. Evers, E. Lenkiewicz, N. H. C. Brons, N. Nicot, A. Oudin, S. Bougnaud, F. Hertel, R. Bjerkvig, M. Barrett, L. Vallar, S. P. Niclou, X. Hao, J. Rahn, E. Ujack, X. Lun, G. Cairncross, S. Weiss, D. Senger, S. Robbins, J. Harness, R. Lerner, Y. Ihara, R. Santos, J. D. L. Torre, A. Lu, T. Ozawa, T. Nicolaides, D. James, C. Petritsch, D. Higgins, M. Schroeder, B. Ball, B. Milligan, F. Meyer, J. Sarkaria, J. Henley, W. Flavahan, Q. Wu, M. Hitomi, N. Rahim, Y. Kim, A. Sloan, R. Weil, I. Nakano, J. Sarkaria, B. Stringer, M. Li, J. Lathia, J. Rich, A. Hjelmeland, M. Kaluzova, S. Platt, M. Kent, A. Bouras, R. Machaidze, C. Hadjipanayis, S.-G. Kang, S.-H. Kim, Y.-M. Huh, E.-H. Kim, E.-K. Park, J. H. Chang, S. H. Kim, Y. K. Hong, D. S. Kim, S.-J. Lee, E. H. Kim, S. G. Kang, M. Hitomi, L. Deleyrolle, M. Sinyuk, M. Li, W. Goan, B. Otvos, M. Rohaus, M. Oli, V. Vedam-Mai, D. Schonberg, Q. Wu, J. Rich, B. Reynolds, J. Lathia, S.-T. Lee, K. Chu, S.-H. Kim, S. K. Lee, M. Kim, J.-K. Roh, R. Lerner, A. Griveau, Y. Ihara, B. Reichholf, M. McMahon, D. Rowitch, D. James, C. Petritsch, R. Nitta, S. Mitra, M. Agarwal, T. Bui, G. Li, J. Lin, C. Adamson, J. Martinez-Quintanilla, S.-H. Choi, D. Bhere, A. Shavkunov, R. Spelat   +201 more
openaire   +3 more sources