Results 131 to 140 of about 627,955 (365)

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

Advanced Science, Volume 12, Issue 18, May 15, 2025.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao, Siwen Chen, Hua Chao, Zihao Li, Hao Yang, Dongying Chen, Sifang Li, Shuai Zhang, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Tangming Guan, Yiwen Zhang, Wende Li, Hui Liu   +16 more
wiley   +1 more source

比较经颅超声造影和数字减影血管造影对大脑中动脉狭窄的诊断价值研究 Diagnostic Value of Transcranial Contrast-enhanced Ultrasound and Digital Subtraction Angiography for Middle Cerebral Artery Stenosis

Zhongguo cuzhong zazhi, 2019
【摘要】 目的 比较经颅超声造影（transcranial contrast-enhanced ultrasound，t-CEUS）和DSA在大脑中动脉（middle cerebral artery，MCA）狭窄性疾病中的诊断价值。 方法 收集2017年12月-2019年4月疑似MCA狭窄或闭塞的患者197例，记录其225条狭窄或闭塞的大脑中动脉的t-CEUS和DSA检查结果。根据MCA狭窄程度分为轻度狭窄（30%～50%），中度狭窄（50%～69%），重度狭窄（70%～99%）和闭塞（100 ...
张惠琴，王立淑，田凤兰，王坤，徐冬娟，何文
doaj   +1 more source

Computational Assessment of Hemodynamics in Asymmetric-type Lesion of Idealized Coronary Stenoses [PDF]

arXiv
Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with varying stenosis configurations, all maintaining an 80% lumen reduction, to determine how differences in morphology
arxiv  

CONGENITAL HYPERTROPHIC PYLORIC STENOSIS AND ITS TREATMENT BY ATROPIN [PDF]

, 1922
Sidney V. Haas
openalex   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Automated vision-based assistance tools in bronchoscopy: stenosis severity estimation [PDF]

arXiv
Purpose: Subglottic stenosis refers to the narrowing of the subglottis, the airway between the vocal cords and the trachea. Its severity is typically evaluated by estimating the percentage of obstructed airway. This estimation can be obtained from CT data or through visual inspection by experts exploring the region.
arxiv  

Stenosis of the naso‐pharynx operation with prosthesis. [PDF]

, 1917
Harry E. Isaacs
openalex   +1 more source

Biomedical Applications of Gadolinium‐Containing Biomaterials: Not Only MRI Contrast Agent

Advanced Science, EarlyView.
This paper summarizes the latest applications and potential mechanisms of the rare earth element gadolinium in biomedical fields, in addition to its traditional application as an MRI contrast agent, including osteogenesis, antimicrobial, antitumor, bioimaging, bioprobes, and so on.
Xingtong Pan, Menglong Hu, Likun Wu, Erfan Wei, Qiyue Zhu, Letian Lv, Xiuyun Xv, Xinyi Dong, Hao Liu, Yunsong Liu   +9 more
wiley   +1 more source

Risk Factor Stratification for Intracranial Stenosis in Taiwanese Patients With Cervicocerebral Stenosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Intracranial stenosis (ICS) is a major determinant of ischemic stroke in Asians. We determined the clinical significance of different risk factors and the role of ICS in Taiwanese patients with varied distributions of cervicocerebral stenosis.
Yueh‐Feng Sung, Jiunn‐Tay Lee, Chia‐Lin Tsai, Chun‐Chieh Lin, Yaw‐Don Hsu, Jiann‐Chyun Lin, Chi‐Ming Chu, Giia‐Sheun Peng   +7 more
doaj   +1 more source

The Opening Snap of the Tricuspid Valve: A Physical Sign of Tricuspid Stenosis [PDF]

, 1955
Charles E. Kossmann
openalex   +1 more source