Results 51 to 60 of about 376,586 (304)

Efficient pollutants removal by amino-modified nanocellulose impregnated with iron oxide [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
A novel adsorbents NC-PEG, obtained by the modification of nanocellulose (NC) with PEG-6-arm amino polyethylene glycol (PEG-NH2) via maleic anhydride (MA) linker, was used for the removal of Cd2+ and Ni2+ from water.
Taleb Khaled A.   +6 more
doaj   +1 more source

UNE PLATE-FORME STEP-NC POUR LA PROGRAMMATION AVANCEE ET INTELLIGENTE DES MACHINES OUTILS [PDF]

open access: yes, 2009
National audienceLa programmation actuelle des machines outils à commandes numériques s'appuie sur le standard ISO 6983, ou code G, dont les principes datent du début des années 60.
Hascoët, Jean-Yves   +2 more
core   +1 more source

Design and implementation of a function block-based holonic control architecture for a new generation flexible manufacturing system [PDF]

open access: yes, 2017
In this research work a control architecture which gives response to the requirements of new generation of flexible manufacturing systems in terms of flexibility, reconfigurability, robustness and autonomy is designed and implemented.
Estruch Ivars, Antonio   +4 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Feature recognition & tool path generation for 5 axis STEP-NC machining of free form / irregular contoured surfaces [PDF]

open access: yes, 2010
This research paper presents a five step algorithm to generate tool paths for machining Free form / Irregular Contoured Surface(s) (FICS) by adopting STEP-NC (AP-238) format. In the first step, a parametrized CAD model with FICS is created or imported in
Anbalagan, A
core   +1 more source

Development of a STEP-compliant design and manufacturing framework for discrete sheet metal bend parts [PDF]

open access: yes, 2016
Metal sheets have the ability to be formed into nonstandard sizes and sections. Displacement-controlled computer numerical control press brakes are used for three-dimensional sheet metal forming.
Ali, Liaqat   +8 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

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