Results 1 to 10 of about 19,948,663 (200)

Step-Up Approach for Sodium Butyrate Treatment in Children With Congenital Chloride Diarrhea [PDF]

Frontiers in Pediatrics, 2022
ObjectivesOral salt substitutive therapy is pivotal for the survival of patients with congenital chloride diarrhea (CLD), however this therapy is unable to influence the symptoms severity.
Lavinia Di Meglio, Lavinia Di Meglio, Giusi Grimaldi, Francesco Esposito, Monica Gelzo, Maria Valeria Esposito, Giuseppe Castaldo, Roberto Berni Canani, Roberto Berni Canani, Roberto Berni Canani   +9 more
doaj   +2 more sources

Gastrointestinal Fistulas in Necrotizing Pancreatitis Receiving a Step-Up Approach Incidence, Risk Factors, Outcomes and Treatment

Journal of Inflammation Research, 2023
Zheyu Liu,1 Huajing Ke,1 Yuwen Xiong,1 Hui Liu,1 Mengli Yue,2 Pi Liu3 1Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 2Affiliated Longhua People’s Hospital, The Third ...
Liu Z, Ke H, Xiong Y, Liu H, Yue M, Liu P   +5 more
doaj   +1 more source

The burden of acute pancreatitis and early experience of step-up approach for acute necrotizing pancreatitis at Military Hospital

Journal of Society of Surgeons of Nepal, 2019
Introduction: Twenty-five percent of acute pancreatitis develops severe acute pancreatitis (SAP). SAP patients have prolonged hospitalization and require a substantial amount of manpower and hospital resources.
Sushil Bahadur Rawal, Uttam Laudari, Basanta Khatiwada, Anup Thapa, Manoj Kumar Jha, Jyoti Rayamajhi, Srijan Malla   +6 more
doaj   +1 more source

Comparison of Different Surgical Methods for Necrotizing Pancreatitis: A Meta-Analysis

Frontiers in Surgery, 2021
Purpose: To compare the effectiveness and safety of three methods of open necrosectomy, minimally invasive surgery and endoscopic step-up approach for necrotizing pancreatitis.Methods: We searched Pubmed, Embase, ScienceDirect, and CNKI full text ...
Jianguo Xiao, Jianguo Xiao, Xiaojiao Quan, Fang Liu, Fang Liu, Wen Li   +5 more
doaj   +1 more source

Endoscopic step up: When and how

Surgery Open Science, 2022
The management of (peri)pancreatic collections has undergone a paradigm shift from open surgical drainage to minimally invasive endoscopic, percutaneous, or surgical interventions.
Vaneet Jearth, MD, DM, Surinder S Rana, MD, DM, FASGE, AGAF   +1 more
doaj   +1 more source

Step-up approach for acute infected necrotizing pancreatitis

Сучасні медичні технології, 2019
Purpose of the study. The role of interventional methods of the treatment of acute infected necrotic pancreatitis depending on the morphological characteristics of the disease was determined. Material and methods.
O. I. Dronov, I. O. Kovalska, A. I. Gorlach, T. V. Lubenets   +3 more
doaj   +1 more source

Impact of prior antibiotics on infected pancreatic necrosis microbiology in ICU patients: a retrospective cohort study

Annals of Intensive Care, 2020
Background Recent guidelines advise against prophylactic antibiotics in patients with necrotizing pancreatitis, advocating instead a step-up drainage and necrosectomy strategy with antibiotics as dictated by microbiological findings.
Charlotte Garret, Emmanuel Canet, Stéphane Corvec, David Boutoille, Matthieu Péron, Isabelle Archambeaud, Aurélie Le Thuaut, Jean-Baptiste Lascarrou, Frédéric Douane, Marc Lerhun, Nicolas Regenet, Emmanuel Coron, Jean Reignier   +12 more
doaj   +1 more source

Escalation to biologics after corticosteroids in patients with newly diagnosed Crohn’s disease in Japan: a claims analysis from 2010 to 2021 [PDF]

Intestinal Research
Background/Aims A previous health insurance claims study of Japanese patients with newly diagnosed Crohn’s disease (CD) reported an increase in “step-up” approach from 2010 to 2020, with biologic use in the first year remaining stable.
Minoru Matsuura, Annabelle Yoon, Jun Miyoshi, Tadakazu Hisamatsu   +3 more
doaj   +1 more source

Postponed or immediate drainage of infected necrotizing pancreatitis (POINTER trial): study protocol for a randomized controlled trial

Trials, 2019
Background Infected necrosis complicates 10% of all acute pancreatitis episodes and is associated with 15–20% mortality. The current standard treatment for infected necrotizing pancreatitis is the step-up approach (catheter drainage, followed, if ...
Janneke van Grinsven, Sven M. van Dijk, Marcel G. Dijkgraaf, Marja A. Boermeester, Thomas L. Bollen, Marco J. Bruno, Sandra van Brunschot, Cornelis H. Dejong, Casper H. van Eijck, Krijn P. van Lienden, Djamila Boerma, Peter van Duijvendijk, Muhammed Hadithi, Jan Willem Haveman, René W. van der Hulst, Jeroen M. Jansen, Daan J. Lips, Eric R. Manusama, I. Quintus Molenaar, Donald L. van der Peet, Alexander C. Poen, Rutger Quispel, Alexander F. Schaapherder, Erik J. Schoon, Matthijs P. Schwartz, Tom C. Seerden, B. W. Marcel Spanier, Jan Willem Straathof, Niels G. Venneman, Wim van de Vrie, Ben J. Witteman, Harry van Goor, Paul Fockens, Hjalmar C. van Santvoort, Marc G. Besselink, for the Dutch Pancreatitis Study Group   +35 more
doaj   +1 more source

“One-step” approach versus “Step-up” approach minimally invasive treatment for infected pancreatic necrosis: a study protocol for a single-center, prospective, randomized controlled trial

BMC Gastroenterology, 2022
Background Currently, the minimally invasive “Step-up” surgical strategy is still the main treatment for infected pancreatic necrosis (IPN). However, indiscriminate implementation of the “Step-up” strategy can lead to increased numbers of operations and ...
Zhi Zheng, Jiongdi Lu, Feng Cao, Yixuan Ding, Yulin Guo, Wentong Mei, Yuanxu Qu, Shuang Liu, Haichen Sun, Yeqing Cui, Ang Li, Fei Li   +11 more
doaj   +1 more source