Results 1 to 10 of about 8,079,547 (292)

A Step-up Approach, or Open Necrosectomy for Necrotizing Pancreatitis [PDF]

New England Journal of Medicine, 2010
Necrotizing pancreatitis with infected necrotic tissue is associated with a high rate of complications and death. Standard treatment is open necrosectomy. The outcome may be improved by a minimally invasive step-up approach.In this multicenter study, we randomly assigned 88 patients with necrotizing pancreatitis and suspected or confirmed infected ...
van Santvoort, Hjalmar C., Besselink, Marc G., Bakker, Olaf J., Hofker, H. Sijbrand, Boermeester, Marja A., Dejong, Cornelis H., van Goor, Harry, Schaapherder, Alexander F., van Eijck, Casper H., Bollen, Thomas L., van Ramshorst, Bert, Nieuwenhuijs, Vincent B., Timmer, Robin, Laméris, Johan S., Kruyt, Philip M., Manusama, Eric R., van der Harst, Erwin, van der Schelling, George P., Karsten, Tom, Hesselink, Eric J., van Laarhoven, Cornelis J., Rosman, Camiel, Bosscha, Koop, de Wit, Ralph J., Houdijk, Alexander P., van Leeuwen, Maarten S., Buskens, Erik, Gooszen, Hein G., Bollen, T. L., Buskens, E., Dejong, C. H., van Eijck, C. H., van Goor, H., Gooszen, H. G., Hofker, H. S., van Leeuwen, M. S., Nieuwenhuijs, V. B., Ploeg, R. J., van Ramshorst, B., Schaapherder, A. F., Timmer, R., Moll, F. L., Moons, K. G., Prokop, M., Ahmed Ali, U., Laméris, W., Gouma, D. J., Busch, O. R., Fockens, P., Bruno, M.   +49 more
core   +19 more sources

Gastrointestinal Fistulas in Necrotizing Pancreatitis Receiving a Step-Up Approach Incidence, Risk Factors, Outcomes and Treatment [PDF]

Journal of Inflammation Research, 2023
Zheyu Liu,1 Huajing Ke,1 Yuwen Xiong,1 Hui Liu,1 Mengli Yue,2 Pi Liu3 1Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 2Affiliated Longhua People’s Hospital, The Third ...
Liu Z, Ke H, Xiong Y, Liu H, Yue M, Liu P   +5 more
doaj   +3 more sources

Step-up approach in emphysematous hepatitis: A case report. [PDF]

World J Hepatol, 2022
Emphysematous hepatitis (EH) is a rare, rapidly progressive fulminant gas-forming infection of the liver parenchyma. It is often fatal and mostly affects diabetes patients.We report a case of EH successfully managed by a step-up approach consisting of aggressive hemodynamic support, intravenous antibiotics, and percutaneous drainage, ultimately ...
Francois S, Aerts M, Reynaert H, Van Lancker R, Van Laethem J, Kunda R, Messaoudi N.   +6 more
europepmc   +4 more sources

A step-up approach to management of complex bronchopleural fistula. [PDF]

J Surg Case Rep, 2022
Abstract Bronchopleural fistula (BPF) is a sinus tract between a mainstem, lobar or segmental bronchus and the pleural space. We present a 68-year-old male with a 13 mm spiculated left lower lobe nodule who underwent video-assisted thoracoscopic surgery left lower lobe wedge resection followed by persistent BPF requiring open window ...
Mazzolini KJ, Dzubnar JM, Velotta JB.
europepmc   +5 more sources

Step-Up Approach for Sodium Butyrate Treatment in Children With Congenital Chloride Diarrhea [PDF]

Frontiers in Pediatrics, 2022
ObjectivesOral salt substitutive therapy is pivotal for the survival of patients with congenital chloride diarrhea (CLD), however this therapy is unable to influence the symptoms severity.
Lavinia Di Meglio, Lavinia Di Meglio, Giusi Grimaldi, Francesco Esposito, Monica Gelzo, Maria Valeria Esposito, Giuseppe Castaldo, Roberto Berni Canani, Roberto Berni Canani, Roberto Berni Canani   +9 more
doaj   +3 more sources

Clinical Outcomes of the Endoscopic Step-Up Approach with or without Radiology-Guided Percutaneous Drainage for Symptomatic Walled-Off Pancreatic Necrosis [PDF]

Medicina, 2023
Background and objectives: Symptomatic walled-off pancreatic necrosis is a serious local complication of acute necrotising pancreatitis. The endoscopic step-up approach is the standard treatment for symptomatic walled-off pancreatic necrosis; however ...
Tanawat Pattarapuntakul, Tummarong Charoenrit, Thanawin Wong, Nisa Netinatsunton, Bancha Ovartlarnporn, Thanapon Yaowmaneerat, Teeravut Tubtawee, Pattira Boonsri, Pimsiri Sripongpun   +8 more
doaj   +3 more sources

Precise pancreatic necrosectomy by step-up approach. [PDF]

EXCLI J, 2021
EXCLI Journal; 20:Doc1305; ISSN 1611 ...
Sundaramurthi S, Kannan A, Nagarajan R, Dasarathan S, Dharanipragada K.   +4 more
europepmc   +4 more sources

WONDER-01: immediate necrosectomy vs. drainage-oriented step-up approach after endoscopic ultrasound-guided drainage of walled-off necrosis—study protocol for a multicentre randomised controlled trial [PDF]

Trials, 2023
Background With the increasing popularity of endoscopic ultrasound (EUS)-guided transmural interventions, walled-off necrosis (WON) of the pancreas is increasingly managed via non-surgical endoscopic interventions.
Tatsuya Sato, Tomotaka Saito, Mamoru Takenaka, Takuji Iwashita, Hideyuki Shiomi, Toshio Fujisawa, Nobuhiko Hayashi, Keisuke Iwata, Akinori Maruta, Tsuyoshi Mukai, Atsuhiro Masuda, Saburo Matsubara, Tsuyoshi Hamada, Tadahisa Inoue, Hiroshi Ohyama, Masaki Kuwatani, Hideki Kamada, Shinichi Hashimoto, Toshiyasu Shiratori, Reiko Yamada, Hirofumi Kogure, Takeshi Ogura, Kazunari Nakahara, Shinpei Doi, Kenji Chinen, Hiroyuki Isayama, Ichiro Yasuda, Yousuke Nakai, for the WONDERFUL study group in Japan, collaborators   +28 more
doaj   +3 more sources

Step-up approach for the treatment of infected necrotising pancreatitis: real life data from a single-centre experience with long-term follow-up [PDF]

BMC Gastroenterology
Background About 20% of patients with acute pancreatitis develop a necrotising form with a worse prognosis due to frequent appearance of organ failure(s) and/or infection of necrosis.
Claire Valentin, Guillaume Le Cosquer, Géraud Tuyeras, Adrian Culetto, Karl Barange, Pierre-Emmanuel Hervieu, Nicolas Carrère, Fabrice Muscari, Fatima Mokrane, Philippe Otal, Barbara Bournet, Bertrand Suc, Louis Buscail   +12 more
doaj   +3 more sources

Walled-off pancreatic necrosis: a staged multidisciplinary step-up approach. [PDF]

BMJ Case Rep, 2020
Walled-off pancreatic necrosis (WOPN) is a rare complication of pancreatitis. We present the case of a woman in her eighties admitted for diffuse abdominal pain. She had a palpable abdominal mass and the CT scan showed necrosis throughout the tail of the pancreas, a peripancreatic and retrogastric hydroaerial collection (19 cm of diameter) and a ...
Sousa D, Freitas Ferreira AC, Raimundo P, Maio R.   +3 more
europepmc   +4 more sources