Results 111 to 120 of about 5,675,091 (285)
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
wiley +1 more source
Competitive policies in the Nordic Energy Research and Innovation Area − eNERGIA: Synthesis report [PDF]
The report is the result of the research project Competitive policies in the Nordic Energy Research and Innovation Area (eNERGIA). The project was co-funded by Nordic Energy Research and NIFU STEP.
Klitkou, Antje +3 more
core
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A hierarchy of environmental covariates control the global biogeography of soil bacterial richness
Soil bacterial communities are central to ecosystem functioning and services, yet spatial variations in their composition and diversity across biomes and climatic regions remain largely unknown.
Samuel Bickel +3 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
glmulti: An R Package for Easy Automated Model Selection with (Generalized) Linear Models
We introduce glmulti, an R package for automated model selection and multi-model inference with glm and related functions. From a list of explanatory variables, the provided function glmulti builds all possible unique models involving these variables and,
Vincent Calcagno, Claire de Mazancourt
doaj
Ressursbruk til forskning og utviklingsarbeid (FoU) i helseforetakene i 2007: Hovedresultater og dokumentasjon [PDF]
Et hovedformål med denne rapporten er å beskrive hovedmønstre i helseforetakenes ressursbruk til forskning og utviklingsarbeid (FoU) i 2007. Beskrivelsen bygger på innrapportert materiale fra helseforetak og private, ideelle sykehus.
Wiig, Ole
core
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

