Results 231 to 240 of about 11,045,758 (299)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Feasibility of performing the 3-minute step test with remote supervision in children and adolescents with cystic fibrosis: A comparative study. [PDF]

Pediatr Investig
Vendrusculo FM, da Costa GA, Bagatini MA, Lemes BMHM, Faria CA, de Oliveira LC, Aquino EDS, Donadio MVF.   +7 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Validity and reliability of the 2-min step test in individuals with stroke and lower-limb musculoskeletal disorders. [PDF]

Front Rehabil Sci
Ishigaki T, Kubo H, Yoshida K, Shimizu N, Ogawa T.   +4 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Intra-rater and test-retest reliability of videography observation method to check diversion time in Fukuda step test among college going students. [PDF]

Phys Act Nutr
Kumar A, Upmanyu A.
europepmc   +1 more source

Measurement properties of the incremental step test for people with chronic obstructive pulmonary disease: a cross-sectional study. [PDF]

BMJ Open
Gonçalves T, Carlos Winck J, Silva F, Caneiras C, Montes AM, Vilarinho R.   +5 more
europepmc   +1 more source

The six-minute step test can predict COPD exacerbations: a 36-month follow-up study. [PDF]

Sci Rep
Santos-de-Araújo AD, da Luz Goulart C, Marinho RS, Dourado IM, Mendes RG, Roscani MG, Bassi-Dibai D, Phillips SA, Arena R, Borghi-Silva A.   +9 more
europepmc   +1 more source

Comment on Bianco et al. Differences in Arrhythmia Detection Between Harvard Step Test and Maximal Exercise Testing in a Paediatric Sports Population. <i>J. Cardiovasc. Dev. Dis.</i> 2025, <i>12</i>, 22. [PDF]

J Cardiovasc Dev Dis
Neunhaeuserer D, Battista F, Quinto G, Degano G, Gasperetti A, Ermolao A.   +5 more
europepmc   +1 more source