Results 91 to 100 of about 136,626 (309)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
For problems that traditional AC voltage regulator is difficult to meet with real-time, precision regulator and voltage stabilization, an automatic control system of three-phase voltage regulating based on single-chip microcomputer was designed ...
XING Yue-hua, FU Lei, XUE Zhang-hua
doaj
Trade-off analysis and design of a Hydraulic Energy Scavenger [PDF]
In the last years there has been a growing interest in intelligent, autonomous devices for household applications. In the near future this technology will be part of our society; sensing and actuating will be integrated in the environment of our houses ...
Boero, Diego +4 more
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A Powerful Optimization Tool for Analog Integrated Circuits Design [PDF]
This paper presents a new optimization tool for analog circuit design. Proposed tool is based on the robust version of the differential evolution optimization method. Corners of technology, temperature, voltage and current supplies are taken into account
Jakovenko, J., Kubar, M.
core +1 more source
Performance estimation of interior permanent-magnet brushless motors using the voltage-driven flux-MMF diagram [PDF]
The flux-magnetomotive force (flux-MMF) diagram, or "energy conversion loop," is a powerful tool for computing the parameters of saturated interior permanent-magnet brushless motors, especially when the assumptions underlying classical dq theory are not ...
Cossar, C. +3 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Pneumatic PID with Ultrasonic Distance Feedback [PDF]
Indiana University Purdue University IndianapolisIndiana University–Purdue University Indianapolis (IUPUI) is initiating a new course to the Electrical & Computer Engineering Technology (ECET) Curriculum in the spring of 2019, this course is Advanced ...
Al Fuhidah, Basim +2 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Switched Capacitor Voltage Converter [PDF]
This project supports IoT development by reducing the power con- sumption and physical footprint of voltage converters. Our switched- capacitor IC design steps down an input of 1:0 - 1:4 V to 0:6 V for a decade of load current from 5 ...
Hsia, Anne, Kidd, Bradford
core +1 more source

