Results 101 to 110 of about 136,626 (309)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Low-noise high-voltage DC power supply for nanopositioning applications [PDF]

open access: yes, 2014
Nanopositioning techniques currently applied to characterize physical properties of materials interesting for applications at the microscopic scale rely on high-voltage electronic control circuits that should have the lowest possible noise level. Here we
Belussi, Cristian H.   +2 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Excitable behaviors

open access: yes, 2017
This chapter revisits the concept of excitability, a basic system property of neurons. The focus is on excitable systems regarded as behaviors rather than dynamical systems.
Drion, Guillaume   +2 more
core  

Output-capacitorless low-dropout regulator for power management applications [PDF]

open access: yes, 2019
This article aims to present the design of a 4.5-V, 450-mA low drop-out (LDO) voltage linear regulator based on a two-stage cascoded operational transconductance amplifier (OTA) as error amplifier.
Martínez García, Herminio
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Development and Application of 16.5 MW High Voltage DC Power Supply

open access: yesKongzhi Yu Xinxi Jishu, 2016
Aiming to the problems such as high harmonic content of output voltage and high output voltage acquired difficultly in the regular AC voltage regulator with the scheme of changing conduction angle of thyristor to adjust AC output voltage directly, a high
LI Hong, YANG Tuoying, CHEN Xiaowu
doaj  

Robust AVR design for the synchronous generator

open access: yesThe Journal of Engineering, 2019
Conventional automatic voltage regulator (AVR) schemes use thyristor-based rectifiers in which the generator field voltage is varied by changing the thyristor's firing angle.
Lamyaa Y. Ghamri   +5 more
doaj   +1 more source

Static inverters which sum a plurality of waves Patent [PDF]

open access: yes, 1970
Describing static inverter with single or multiple phase ...
Anderson, D. L.   +3 more
core   +1 more source

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