Results 1 to 10 of about 19,189 (142)

Stepped wedge cluster randomised trials: a review of the statistical methodology used and available [PDF]

BMC Medical Research Methodology, 2016
Background Previous reviews have focussed on the rationale for employing the stepped wedge design (SWD), the areas of research to which the design has been applied and the general characteristics of the design.
D. Barker, P. McElduff, C. D’Este, M. J. Campbell   +3 more
doaj   +5 more sources

Designing stepped wedge trials to evaluate physical activity interventions in schools: methodological considerations [PDF]

International Journal of Behavioral Nutrition and Physical Activity
Background In a stepped wedge design, schools are randomised to a sequence of measurements, with each sequence transitioning to intervention status at a different time.
Ruth Salway, Danielle House, Simona Kent-Saisch, Robert Walker, Lydia Emm-Collison, Alice Porter, David R Lubans, Michael Beets, Frank de Vocht, Russell Jago   +9 more
doaj   +2 more sources

Stepped-wedge randomised trial of laparoscopic ventral mesh rectopexy in adults with chronic constipation: study protocol for a randomized controlled trial [PDF]

Trials, 2018
Background Laparoscopic ventral mesh rectopexy (LVMR) is an established treatment for external full-thickness rectal prolapse. However, its clinical efficacy in patients with internal prolapse is uncertain due to the lack of high-quality evidence ...
Ugo Grossi, Natasha Stevens, Eleanor McAlees, Jon Lacy-Colson, Steven Brown, Anthony Dixon, Gian Luca Di Tanna, S. Mark Scott, Christine Norton, Nadine Marlin, James Mason, Charles H. Knowles, On behalf of the NIHR CapaCiTY working group   +12 more
doaj   +3 more sources

Method and reporting guideline for stepped-wedge trials

Zhongguo gonggong weisheng, 2022
Stepped-wedge trial is an emerging cluster randomized controlled trial in the field of service provision and policy evaluation, which is becoming increasingly popular among health care researchers in recent years.
Hua-xin SI, Xiao-xia QIAO, Ya-ru JIN
doaj   +1 more source

The unrecognized role of fidelity in effectiveness-implementation hybrid trials: simulation study and guidance for implementation researchers

BMC Medical Research Methodology, 2023
Background Effectiveness-implementation hybrid designs are a relatively new approach to evaluate efficacious interventions in real-world settings while concurrently gathering information on the implementation.
Diana Trutschel, Catherine Blatter, Michael Simon, Daniela Holle, Sven Reuther, Thekla Brunkert   +5 more
doaj   +1 more source

Design, rationale and analysis plan for the Stand Up for Health trial in contact centres: a stepped wedge feasibility study

Pilot and Feasibility Studies, 2020
Background Contact centres are one of the most sedentary workplaces, with employees spending a very high proportion of their working day sitting down.
Richard A. Parker, Jillian Manner, Divya Sivaramakrishnan, Graham Baker, Andrew Stoddart, Scott Lloyd, Ruth Jepson   +6 more
doaj   +1 more source

Novel Ordered Stepped-Wedge Cluster Trial Designs for Detecting Ebola Vaccine Efficacy Using a Spatially Structured Mathematical Model. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:During the 2014 Ebola virus disease (EVD) outbreak, policy-makers were confronted with difficult decisions on how best to test the efficacy of EVD vaccines.
Ibrahim Diakite, Eric Q Mooring, Gustavo E Velásquez, Megan B Murray   +3 more
doaj   +1 more source

The stepped wedge trial design: a systematic review

BMC Medical Research Methodology, 2006
Background Stepped wedge randomised trial designs involve sequential roll-out of an intervention to participants (individuals or clusters) over a number of time periods.
Lilford Richard J, Brown Celia A
doaj   +1 more source

Point-of-care ultrasound-guided regional anaesthesia in older ED patients with hip fractures: a study to test the feasibility of a training programme and time needed to complete nerve blocks by ED physicians after training

BMJ Open, 2021
Objectives Point-of-care ultrasound-guided regional anaesthesia (POCUS-GRA) provides safe, rapid analgesia for older people with hip fractures but is rarely performed in the emergency department (ED).
Debra Eagles, Eddy Lang, Marcel Émond, Alex Kiss, Shelley L McLeod, Jordan Chenkin, Bjug Borgundvaag, Andrew D McRae, Jacques Simon Lee, Tina Bhandari, Robert Simard, Claude Topping, Michael Woo, Jeffrey Perry, Charles Wong, Marco Sivilotti, Joseph Newbigging, Donald Melady, Lan Chernoff   +18 more
doaj   +1 more source

Group sequential designs for stepped-wedge cluster randomised trials. [PDF]

, 2017
BACKGROUND/AIMS: The stepped-wedge cluster randomised trial design has received substantial attention in recent years. Although various extensions to the original design have been proposed, no guidance is available on the design of stepped-wedge cluster ...
Grayling, Michael J, Mander, Adrian P, Wason, James Ms   +2 more
core   +1 more source