Effectiveness of Seasonal Malaria Chemoprevention in children under 10 years of age in Senegal: a stepped-wedge cluster-randomized trial [PDF]
This study was done to determine the effectiveness of Seasonal Malaria Chemoprevention in Senegalese children up to 10 years of age using a stepped-wedge design.
Milligan, Paul
core +2 more sources
The impact of varying cluster size in cross-sectional stepped-wedge cluster randomised trials
Background Cluster randomised trials with unequal sized clusters often have lower precision than with clusters of equal size. To allow for this, sample sizes are inflated by a modified version of the design effect for clustering.
James Thomas Martin +2 more
doaj +1 more source
Background Stepped wedge trials are an appealing and potentially powerful cluster randomized trial design. However, they are frequently implemented with a small number of clusters.
Kelsey L. Grantham +4 more
doaj +1 more source
Impact of early initiation versus national standard of care of antiretroviral therapy in Swaziland's public sector health system : study protocol for a stepped-wedge randomized trial [PDF]
Background: There is robust clinical evidence to support offering early access to antiretroviral treatment (ART) to all HIV-positive individuals, irrespective of disease stage, to both improve patient health outcomes and reduce HIV incidence. However, as
Barnighausen, Till +11 more
core +5 more sources
Applying thematic synthesis to interpretation and commentary in epidemiological studies: identifying what contributes to successful interventions to promote hand hygiene in patient care [PDF]
Objectives: Hand hygiene is considered the most important preventive measure for healthcare associated infections, but adherence is suboptimal. We previously undertook a Cochrane Review which demonstrated that interventions to improve adherence are ...
Birgand +9 more
core +2 more sources
Background A pragmatic, stepped wedge trial design can be an appealing design to evaluate complex interventions in real-life settings. However, there are certain pitfalls that need to be considered.
Noor Heim +5 more
doaj +1 more source
Design of trials for interrupting the transmission of endemic pathogens [PDF]
Many interventions against infectious diseases have geographically diffuse effects. This leads to contamination between arms in cluster-randomized trials (CRTs).
Hiscox, Alexandra +6 more
core +3 more sources
Field efficacy evaluation and post-treatment contamination risk assessment of an ultraviolet disinfection and safe storage system. [PDF]
Inconsistent use of household water treatment and safe storage (HWTS) systems reduces their potential health benefits. Ultraviolet (UV) disinfection is more convenient than some existing HWTS systems, but it does not provide post-treatment residual ...
Gruber, Joshua S +3 more
core +2 more sources
The effect of a postpartum IUD intervention on counseling and choice: Evidence from a cluster-randomized stepped-wedge trial in Sri Lanka [PDF]
BACKGROUND: The International Federation of Gynaecology and Obstetrics (FIGO), in collaboration with the Sri Lankan College of Obstetrics and Gynaecologists (SLCOG), launched an initiative in 2014 to institutionalize immediate postpartum IUD (PPIUD ...
Canning, David +8 more
core +1 more source
This paper presents results of numerical calculations for the rolling process by means of three tools of stepped shafts from aluminum alloy 7075. Forming with the usage of tools with three different wedge spreading angles underwent analysis. In the paper,
Bartnicki J., Tomczak J., Pater Z.
doaj +1 more source

