Implementation of a batched stepped wedge trial evaluating a quality improvement intervention for surgical teams to reduce anastomotic leak after right colectomy [PDF]
Trials, 2023 Background Large-scale quality improvement interventions demand robust trial designs with flexibility for delivery in different contexts, particularly during a pandemic.
Mary L. Venn +6 more
doaj +2 more sources
Major influencing factors on routine implementation of shared decision-making in cancer care: qualitative process evaluation of a stepped-wedge cluster randomized trial [PDF]
BMC Health Services Research, 2023 Background Shared decision-making (SDM) is highly relevant in oncology but rarely implemented in routine care. In a stepped-wedge cluster randomized implementation trial, the outcome evaluation of a theoretically and empirically based multi-component SDM
Pola Hahlweg +7 more
doaj +2 more sources
Implementation of an evidence-based management algorithm for patients with chronic pancreatitis (COMBO trial): study protocol for a stepped-wedge cluster-randomized controlled trial [PDF]
Trials, 2023 Background Chronic pancreatitis (CP) is an inflammatory disease that may be complicated by abdominal pain, pancreatic dysfunction, nutritional deficiencies, and diminished bone density.
Florence E. M. de Rijk +10 more
doaj +2 more sources
Divergent confidence intervals among pre-specified analyses in the HiSTORIC stepped wedge trial: An exploratory post-hoc investigation. [PDF]
PLoS ONE, 2022 BackgroundThe high-sensitivity cardiac troponin on presentation to rule out myocardial infarction (HiSTORIC) study was a stepped-wedge cluster randomised trial with long before-and-after periods, involving seven hospitals across Scotland.
Richard A Parker +4 more
doaj +2 more sources
Stepped-wedge randomised trial of laparoscopic ventral mesh rectopexy in adults with chronic constipation: study protocol for a randomized controlled trial [PDF]
Trials, 2018 Background Laparoscopic ventral mesh rectopexy (LVMR) is an established treatment for external full-thickness rectal prolapse. However, its clinical efficacy in patients with internal prolapse is uncertain due to the lack of high-quality evidence ...
Ugo Grossi +12 more
doaj +3 more sources
Multimodal prehabilitation (Fit4Surgery) in high-impact surgery to enhance surgical outcomes: Study protocol of F4S PREHAB, a single center stepped wedge trial. [PDF]
PLoS ONEBackgroundHigh-impact surgery imposes a significant physiological and functional burden and is associated with substantial postoperative morbidity.
Dieuwke Strijker +12 more
doaj +2 more sources
Crowdsourcing to promote HIV testing among MSM in China: study protocol for a stepped wedge randomized controlled trial [PDF]
Trials, 2017 Background HIV testing for marginalized populations is critical to controlling the HIV epidemic. However, the HIV testing rate among men who have sex with men (MSM) in China remains low. Crowdsourcing, the process of shifting individual tasks to a group,
SESH Study Group, Joseph D. Tucker
doaj +2 more sources
Communities Helping the Hearing of Infants by Reaching Parents (CHHIRP) through patient navigation: a hybrid implementation effectiveness stepped wedge trial protocol. [PDF]
BMJ Open, 2022 Bush M +10 more
europepmc +3 more sources
Method and reporting guideline for stepped-wedge trials
Zhongguo gonggong weisheng, 2022 Stepped-wedge trial is an emerging cluster randomized controlled trial in the field of service provision and policy evaluation, which is becoming increasingly popular among health care researchers in recent years.
Hua-xin SI, Xiao-xia QIAO, Ya-ru JIN
doaj +1 more source
Novel Ordered Stepped-Wedge Cluster Trial Designs for Detecting Ebola Vaccine Efficacy Using a Spatially Structured Mathematical Model. [PDF]
PLoS Neglected Tropical Diseases, 2016 BACKGROUND:During the 2014 Ebola virus disease (EVD) outbreak, policy-makers were confronted with difficult decisions on how best to test the efficacy of EVD vaccines.
Ibrahim Diakite +3 more
doaj +1 more source