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The stepped wedge trial design: a systematic review [PDF]
BMC Medical Research Methodology, 2006 Background Stepped wedge randomised trial designs involve sequential roll-out of an intervention to participants (individuals or clusters) over a number of time periods.
Lilford Richard J, Brown Celia A
doaj +3 more sources
Sample size calculation for a stepped wedge trial. [PDF]
Trials, 2015 BACKGROUND: Stepped wedge trials (SWTs) can be considered as a variant of a clustered randomised trial, although in many ways they embed additional complications from the point of view of statistical design and analysis.
Ambler, Gareth +5 more
core +7 more sources
Group sequential designs for stepped-wedge cluster randomised trials. [PDF]
Clinical Trials, 2017 BACKGROUND/AIMS: The stepped-wedge cluster randomised trial design has received substantial attention in recent years. Although various extensions to the original design have been proposed, no guidance is available on the design of stepped-wedge cluster ...
Grayling, Michael J +2 more
core +5 more sources
Five questions to consider before conducting a stepped wedge trial. [PDF]
Trials, 2015 Researchers should consider five questions before starting a stepped wedge trial. Why are you planning one? Researchers sometimes think that stepped wedge trials are useful when there is little doubt about the benefit of the intervention being tested ...
Baio, G +9 more
core +9 more sources
How important is randomisation in a stepped wedge trial? [PDF]
Trials, 2015 In cluster randomised trials, randomisation increases internal study validity. If enough clusters are randomised, an unadjusted analysis should be unbiased.
Copas, Andrew J +3 more
core +5 more sources
Power Analysis for Stepped Wedge Trials with Two Treatments [PDF]
, 2020 AbstractStepped wedge designs (SWDs) are designs for cluster randomized trials that feature staggered, unidirectional cross-over, typically from a control to a treatment condition. Existing literature on statistical power for SWDs primarily focuses on designs with a single treatment.
Phillip Sundin, Catherine M. Crespi
openalex +4 more sources
Key concepts in clinical epidemiology: Stepped wedge trials [PDF]
Journal of Clinical Epidemiology, 2021 A stepped wedge trial evaluates an intervention that is implemented over a number of time periods according to a staggered timetable. Stepped wedge trials are usually cluster randomized, the intervention being delivered at some geographical, service or other cluster level.
openaire +3 more sources
Improving HPV Vaccination Rates: A Stepped-Wedge Randomized Trial [PDF]
Pediatrics, 2020 OBJECTIVES: To evaluate the effectiveness of a stepped-wedge randomized trial of Development of Systems and Education for Human Papillomavirus Vaccination (DOSE HPV), a multilevel intervention. METHODS:
Rebecca B, Perkins +13 more
openaire +2 more sources
Admissible multiarm stepped‐wedge cluster randomized trial designs [PDF]
Statistics in Medicine, 2018 Numerous publications have now addressed the principles of designing, analyzing, and reporting the results of stepped‐wedge cluster randomized trials. In contrast, there is little research available pertaining to the design and analysis of multiarm stepped‐wedge cluster randomized trials, utilized to evaluate the effectiveness of multiple experimental ...
Grayling, Michael J +2 more
openaire +5 more sources
Pilot and Feasibility Studies, 2020 Background Contact centres are one of the most sedentary workplaces, with employees spending a very high proportion of their working day sitting down.
Richard A. Parker +6 more
doaj +1 more source