Results 21 to 30 of about 31,328 (346)

Community participatory learning and action cycle groups to reduce type 2 diabetes in Bangladesh (D:Clare): an updated study protocol for a parallel arm cluster randomised controlled trial

Trials, 2023
The “Diabetes: Community-led Awareness, Response and Evaluation” (D:Clare) trial aims to scale up and replicate an evidence-based participatory learning and action cycle intervention in Bangladesh, to inform policy on population-level T2DM prevention and
Carina King, Malini Pires, Naveed Ahmed, Kohenour Akter, Abdul Kuddus, Andrew Copas, Hassan Haghparast-Bidgoli, Joanna Morrison, Tasmin Nahar, Sanjit Kumer Shaha, AKAzad Khan, Kishwar Azad, Edward Fottrell   +12 more
doaj   +1 more source

The batched stepped wedge design: A design robust to delays in cluster recruitment [PDF]

, 2022
Stepped wedge designs are an increasingly popular variant of longitudinal cluster randomized trial designs, and roll out interventions across clusters in a randomized, but step‐wise fashion. In the standard stepped wedge design, assumptions regarding the
Bowden, R, Forbes, AB, Hooper, R, Kasza, J   +3 more
core   +1 more source

Response adaptive intervention allocation in stepped‐wedge cluster randomized trials

Statistics in Medicine, 2022
BackgroundStepped‐wedge cluster randomized trial (SW‐CRT) designs are often used when there is a desire to provide an intervention to all enrolled clusters, because of a belief that it will be effective. However, given there should be equipoise at trial commencement, there has been discussion around whether a pre‐trial decision to provide the ...
Grayling, Michael J, Wason, James MS, Villar, Sofía S   +2 more
openaire   +5 more sources

Sustainable waiting time reductions after introducing the STAT model for access and triage: 12-month follow up of a stepped wedge cluster randomised controlled trial

BMC Health Services Research, 2020
Background Timely access is a challenge for providers of outpatient and community-based health services, as seen by the often lengthy waiting lists to manage demand.
Katherine E. Harding, David A. Snowdon, Luke Prendergast, Annie K. Lewis, Bridie Kent, Sandy F. Leggat, Nicholas F. Taylor   +6 more
doaj   +1 more source

The unrecognized role of fidelity in effectiveness-implementation hybrid trials: simulation study and guidance for implementation researchers

BMC Medical Research Methodology, 2023
Background Effectiveness-implementation hybrid designs are a relatively new approach to evaluate efficacious interventions in real-world settings while concurrently gathering information on the implementation.
Diana Trutschel, Catherine Blatter, Michael Simon, Daniela Holle, Sven Reuther, Thekla Brunkert   +5 more
doaj   +1 more source

Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches. [PDF]

, 2015
BACKGROUND: There is limited guidance on the design of stepped wedge cluster randomised trials. Current methodological literature focuses mainly on trials with cross-sectional data collection at discrete times, yet many recent stepped wedge trials do not
Baio, Gianluca, Copas, Andrew J, Davey, Calum, Hargreaves, James R, Lewis, James J, Thompson, Jennifer A   +5 more
core   +5 more sources

Delaying and withholding interventions: ethics and the stepped wedge trial [PDF]

Journal of Medical Ethics, 2019
Ethics has been identified as a central reason for choosing the stepped wedge trial over other kinds of trial designs. The potential advantage of the stepped wedge design is that it provides all arms of the trial with the active intervention over the course of the study.
Ariella Binik
openalex   +3 more sources

The optimal design of stepped wedge trials with equal allocation to sequences and a comparison to other trial designs. [PDF]

, 2017
Background/Aims We sought to optimise the design of stepped wedge trials with an equal allocation of clusters to sequences and explored sample size comparisons with alternative trial designs.
Copas, Andrew, Fielding, Katherine, Hargreaves, James, Thompson, Jennifer A   +3 more
core   +2 more sources

Adapting and pilot testing an HIV and intersectional stigma reducing intervention for Dominican Republic healthcare contexts: Protocol for translational research

Contemporary Clinical Trials Communications, 2022
Background: This protocol details the adaptation and pilot testing of the Finding Respect and Ending Stigma around HIV (FRESH) intervention in Dominican Republic.
Henna Budhwani, Robert Paulino-Ramírez, John Waters, Christyenne L. Bond, Ingrid Ruiz, Dustin M. Long, Nelson Varas-Díaz, Sylvie Naar, Laura Nyblade, Janet M. Turan   +9 more
doaj   +1 more source

Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014. [PDF]

, 2015
BACKGROUND: In a stepped wedge, cluster randomised trial, clusters receive the intervention at different time points, and the order in which they received it is randomised. Previous systematic reviews of stepped wedge trials have documented a steady rise
Baio, Gianluca, Beard, Emma, Copas, Andrew, Davey, Calum, Fielding, Katherine L, Hargreaves, James, Lewis, James J, Omar, Rumana Z, Ononge, Sam, Osrin, David, Prost, Audrey, Thompson, Jennifer A   +11 more
core   +2 more sources