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Design and analysis of stepped wedge cluster randomized trials
Contemporary Clinical Trials, 2007Cluster randomized trials (CRT) are often used to evaluate therapies or interventions in situations where individual randomization is not possible or not desirable for logistic, financial or ethical reasons. While a significant and rapidly growing body of literature exists on CRTs utilizing a "parallel" design (i.e.
Michael A, Hussey, James P, Hughes
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Information Content of Cluster–Period Cells in Stepped Wedge Trials
Biometrics, 2018Summary Stepped wedge and other multiple-period cluster randomized trials, which collect data from multiple clusters across multiple time periods, are being conducted with increasing frequency; statistical research into these designs has not kept apace.
Jessica Kasza, Andrew B. Forbes
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Analysis of Data from a Stepped Wedge Trial
2021In this chapter the different methods for the analysis of data from a stepped wedge trial are discussed. These methods contain the comparison of different arms, the comparison of groups with a different number of intervention measurement, and the comparison of transitions.
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TVZ - Verpleegkunde in praktijk en wetenschap, 2021
Janneke de Man-Van Ginkel, Roelof Ettema
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Janneke de Man-Van Ginkel, Roelof Ettema
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ORIENT stepped wedge trial statistical analysis plan
The statistical analysis plan to inform analysis of the ORIENT trial (ANZCTR Identifier: ACTRN12622000086763)Kasza, Jessica +4 more
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What Is a Stepped-Wedge Cluster Randomized Trial?
JAMA Internal MedicineThis Guide to Statistics and Methods describes design, interpretation, and examples of a stepped-wedge cluster randomized trial.
Fan, Li +2 more
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Robust analysis of stepped wedge trials using composite likelihood models
Statistics in MedicineStepped wedge trials (SWTs) are a type of cluster randomized trial that involve repeated measures on clusters and design‐induced confounding between time and treatment. Although mixed models are commonly used to analyze SWTs, they are susceptible to misspecification particularly for cluster‐longitudinal designs such as SWTs.
Emily C. Voldal +4 more
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Scaling Care Coordination Through Digital Engagement: Stepped-Wedge Trial Assessing Readmissions
The American Journal of Managed CareTransitions of care are pivotal, vulnerable times as patients are discharged from the hospital. Telephonic care coordination is standard care, but labor intensive. We implemented a patient postdischarge digital engagement (PDDE) program to scale coordination.
Alexandra, Polovneff +9 more
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Improving antibiotic stewardship: a stepped-wedge cluster randomized trial.
The American journal of managed care, 2018Antibiotic stewardship is key to optimizing patient outcomes and affordable care. The study objective was to examine the effect of provider education and clinical decision support (CDS) on antibiotic prescribing for acute sinusitis among providers of varying experience.A stepped-wedge cluster randomized intervention to evaluate antibiotic use for acute
Adam L, Sharp +6 more
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Stepped-wedge trial design to evaluate Ebola treatments
The Lancet Infectious Diseases, 2015Jolanta, Piszczek, Eric, Partlow
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