Results 11 to 20 of about 43,887 (283)

Sample size calculation for a stepped wedge trial. [PDF]

Trials, 2015
BACKGROUND: Stepped wedge trials (SWTs) can be considered as a variant of a clustered randomised trial, although in many ways they embed additional complications from the point of view of statistical design and analysis.
Ambler, Gareth, Baio, Gianluca, Beard, Emma, Copas, Andrew, Hargreaves, James, Omar, Rumana Z   +5 more
core   +7 more sources

Group sequential designs for stepped-wedge cluster randomised trials. [PDF]

Clinical Trials, 2017
BACKGROUND/AIMS: The stepped-wedge cluster randomised trial design has received substantial attention in recent years. Although various extensions to the original design have been proposed, no guidance is available on the design of stepped-wedge cluster ...
Grayling, Michael J, Mander, Adrian P, Wason, James Ms   +2 more
core   +5 more sources

Micromachine Wedge Stepping Motor [PDF]

Micro-Electro-Mechanical Systems (MEMS), 1998
Abstract A wedge stepping motor, which will index a mechanism, has been designed and fabricated in the surface micromachine SUMMiT (Sandia Ultra-planar Multi-level MEMS Technology) [1] process. This device has demonstrated the ability to index one gear tooth at a time with speeds up to 205 teeth/sec.
Allen, James J., Schriner, Heather K.
openaire   +1 more source

Implementation of a batched stepped wedge trial evaluating a quality improvement intervention for surgical teams to reduce anastomotic leak after right colectomy

Trials, 2023
Background Large-scale quality improvement interventions demand robust trial designs with flexibility for delivery in different contexts, particularly during a pandemic.
Mary L. Venn, Charles H. Knowles, Elizabeth Li, James Glasbey, Dion G. Morton, Richard Hooper, ESCP EAGLE Safe Anastomosis Collaborative   +6 more
doaj   +1 more source

Increasing smear positive tuberculosis detection using a clinical score – A stepped wedge multicenter trial from Africa

International Journal of Infectious Diseases, 2021
Background: The Bandim TBscore is a clinical score that predicts treatment outcome in Tuberculosis (TB) patients and proved useful as an indicator of which healthcare-seeking adults to refer for sputum smear microcopy.
Frauke Rudolf, Ebba Abate, Binyam Moges, Antonio Mateus Mendes, Mezgebu Yitayal Mengistu, Armando Sifna, Hikma Fekadu, Segenet Bizuneh, Thomas Schön, Christian Wejse   +9 more
doaj   +1 more source

Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014. [PDF]

, 2015
BACKGROUND: In a stepped wedge, cluster randomised trial, clusters receive the intervention at different time points, and the order in which they received it is randomised. Previous systematic reviews of stepped wedge trials have documented a steady rise
Baio, Gianluca, Beard, Emma, Copas, Andrew, Davey, Calum, Fielding, Katherine L, Hargreaves, James, Lewis, James J, Omar, Rumana Z, Ononge, Sam, Osrin, David, Prost, Audrey, Thompson, Jennifer A   +11 more
core   +2 more sources

Optimal Design and Analysis of the Cooled Turbine Blade in Gas Turbines with CFD [PDF]

Journal of Applied Fluid Mechanics
In this study, the effects of the structural geometries of the channels used for cooling blades in the heated regions of the gas turbine exposed to high temperature were investigated.
E. Yildiz, F. Koca, I. Can
doaj   +1 more source

Implementation of a stepped wedge cluster randomized trial to evaluate a hospital mobility program

Trials, 2020
Background Stepped wedge cluster randomized trials (SW-CRT) are increasingly used to evaluate new clinical programs, yet there is limited guidance on practical aspects of applying this design.
Susan N. Hastings, Karen M. Stechuchak, Ashley Choate, Elizabeth P. Mahanna, Courtney Van Houtven, Kelli D. Allen, Virginia Wang, Nina Sperber, Leah Zullig, Hayden B. Bosworth, Cynthia J. Coffman   +10 more
doaj   +1 more source

A pragmatic, multi-centered, stepped wedge, cluster randomized controlled trial pilot of the clinical and cost effectiveness of a complex Stroke Oral healthCare intervention pLan Evaluation II (SOCLE II) compared with usual oral healthcare in stroke wards [PDF]

, 2019
BACKGROUND: Patients with stroke-associated pneumonia experience poorer outcomes (increased hospital stays, costs, discharge dependency, and risk of death).
Bain, Brenda Jean, Barr, John, Bowers, Naomi, Brady, Marian C., Chalmers, Campbell, Colins, Marissa, Gray, Heather, Keerie, Catriona, Langhorne, Peter, Pollock, Alex, Stott, David J., Sweeney, Petrina, Weir, Christopher J.   +12 more
core   +2 more sources

Divergent confidence intervals among pre-specified analyses in the HiSTORIC stepped wedge trial: An exploratory post-hoc investigation.

PLoS ONE, 2022
BackgroundThe high-sensitivity cardiac troponin on presentation to rule out myocardial infarction (HiSTORIC) study was a stepped-wedge cluster randomised trial with long before-and-after periods, involving seven hospitals across Scotland.
Richard A Parker, Catriona Keerie, Christopher J Weir, Atul Anand, Nicholas L Mills   +4 more
doaj   +1 more source