Results 21 to 30 of about 44,113 (283)
PLoS ONE, 2022 BackgroundThe high-sensitivity cardiac troponin on presentation to rule out myocardial infarction (HiSTORIC) study was a stepped-wedge cluster randomised trial with long before-and-after periods, involving seven hospitals across Scotland.
Richard A Parker +4 more
doaj +1 more source
Five questions to consider before conducting a stepped wedge trial. [PDF]
, 2015 Researchers should consider five questions before starting a stepped wedge trial. Why are you planning one? Researchers sometimes think that stepped wedge trials are useful when there is little doubt about the benefit of the intervention being tested ...
Baio, G +9 more
core +4 more sources
Admissible multiarm stepped‐wedge cluster randomized trial designs [PDF]
Statistics in Medicine, 2018 Numerous publications have now addressed the principles of designing, analyzing, and reporting the results of stepped‐wedge cluster randomized trials. In contrast, there is little research available pertaining to the design and analysis of multiarm stepped‐wedge cluster randomized trials, utilized to evaluate the effectiveness of multiple experimental ...
Grayling, Michael J +2 more
openaire +5 more sources
Key concepts in clinical epidemiology: Stepped wedge trials [PDF]
Journal of Clinical Epidemiology, 2021 A stepped wedge trial evaluates an intervention that is implemented over a number of time periods according to a staggered timetable. Stepped wedge trials are usually cluster randomized, the intervention being delivered at some geographical, service or other cluster level.
openaire +3 more sources
Trials, 2023 The “Diabetes: Community-led Awareness, Response and Evaluation” (D:Clare) trial aims to scale up and replicate an evidence-based participatory learning and action cycle intervention in Bangladesh, to inform policy on population-level T2DM prevention and
Carina King +12 more
doaj +1 more source
The optimal design of stepped wedge trials with equal allocation to sequences and a comparison to other trial designs. [PDF]
, 2017 Background/Aims We sought to optimise the design of stepped wedge trials with an equal allocation of clusters to sequences and explored sample size comparisons with alternative trial designs.
Copas, Andrew +3 more
core +2 more sources
How important is randomisation in a stepped wedge trial? [PDF]
, 2015 In cluster randomised trials, randomisation increases internal study validity. If enough clusters are randomised, an unadjusted analysis should be unbiased.
Copas, Andrew J +3 more
core +1 more source
BMC Medical Research Methodology, 2016 Background Stepped wedge designs have gained recognition as a method for rigorously assessing implementation of evidence-based quality improvement interventions (QIIs) across multiple healthcare sites.
Alexis K. Huynh +3 more
doaj +1 more source
Indicator-focussed technical assistance in South Africa’s HIV programme: A stepped-wedge evaluation
Southern African Journal of HIV Medicine, 2021 Background: There is a lack of research on technical assistance (TA) interventions in low- and middle-income countries. Variation in local contexts requires tailor-made approaches to TA that are structured and replicable across intervention sites whilst ...
Geoffrey A. Jobson +7 more
doaj +1 more source
Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies [PDF]
, 2015 Background: Three arguments are usually invoked in favour of stepped wedge cluster randomised controlled trials: the logistic convenience of implementing an intervention in phases, the ethical benefit of providing the intervention to all clusters, and ...
Abubakar, Ibrahim +9 more
core +5 more sources