Results 1 to 10 of about 6,729 (263)

Implementation of a batched stepped wedge trial evaluating a quality improvement intervention for surgical teams to reduce anastomotic leak after right colectomy [PDF]

Trials, 2023
Background Large-scale quality improvement interventions demand robust trial designs with flexibility for delivery in different contexts, particularly during a pandemic.
Mary L. Venn, Charles H. Knowles, Elizabeth Li, James Glasbey, Dion G. Morton, Richard Hooper, ESCP EAGLE Safe Anastomosis Collaborative   +6 more
doaj   +2 more sources

Method and reporting guideline for stepped-wedge trials

Zhongguo gonggong weisheng, 2022
Stepped-wedge trial is an emerging cluster randomized controlled trial in the field of service provision and policy evaluation, which is becoming increasingly popular among health care researchers in recent years.
Hua-xin SI, Xiao-xia QIAO, Ya-ru JIN
doaj   +2 more sources

The stepped wedge trial design: a systematic review [PDF]

BMC Medical Research Methodology, 2006
Background Stepped wedge randomised trial designs involve sequential roll-out of an intervention to participants (individuals or clusters) over a number of time periods.
Lilford Richard J, Brown Celia A
doaj   +3 more sources

Divergent confidence intervals among pre-specified analyses in the HiSTORIC stepped wedge trial: An exploratory post-hoc investigation. [PDF]

PLoS ONE, 2022
BackgroundThe high-sensitivity cardiac troponin on presentation to rule out myocardial infarction (HiSTORIC) study was a stepped-wedge cluster randomised trial with long before-and-after periods, involving seven hospitals across Scotland.
Richard A Parker, Catriona Keerie, Christopher J Weir, Atul Anand, Nicholas L Mills   +4 more
doaj   +2 more sources

Multimodal prehabilitation (Fit4Surgery) in high-impact surgery to enhance surgical outcomes: Study protocol of F4S PREHAB, a single center stepped wedge trial. [PDF]

PLoS ONE
BackgroundHigh-impact surgery imposes a significant physiological and functional burden and is associated with substantial postoperative morbidity.
Dieuwke Strijker, Luuk Drager, Monique van Asseldonk, Femke Atsma, Manon van den Berg, Elke van Daal, Linda van Heusden-Scholtalbers, Jeroen Meijerink, Petra Servaes, Steven Teerenstra, Sjors Verlaan, Baukje van den Heuvel, Kees van Laarhoven   +12 more
doaj   +2 more sources

Design, rationale and analysis plan for the Stand Up for Health trial in contact centres: a stepped wedge feasibility study

Pilot and Feasibility Studies, 2020
Background Contact centres are one of the most sedentary workplaces, with employees spending a very high proportion of their working day sitting down.
Richard A. Parker, Jillian Manner, Divya Sivaramakrishnan, Graham Baker, Andrew Stoddart, Scott Lloyd, Ruth Jepson   +6 more
doaj   +1 more source

Community participatory learning and action cycle groups to reduce type 2 diabetes in Bangladesh (D:Clare): an updated study protocol for a parallel arm cluster randomised controlled trial

Trials, 2023
The “Diabetes: Community-led Awareness, Response and Evaluation” (D:Clare) trial aims to scale up and replicate an evidence-based participatory learning and action cycle intervention in Bangladesh, to inform policy on population-level T2DM prevention and
Carina King, Malini Pires, Naveed Ahmed, Kohenour Akter, Abdul Kuddus, Andrew Copas, Hassan Haghparast-Bidgoli, Joanna Morrison, Tasmin Nahar, Sanjit Kumer Shaha, AKAzad Khan, Kishwar Azad, Edward Fottrell   +12 more
doaj   +1 more source

Sustainable waiting time reductions after introducing the STAT model for access and triage: 12-month follow up of a stepped wedge cluster randomised controlled trial

BMC Health Services Research, 2020
Background Timely access is a challenge for providers of outpatient and community-based health services, as seen by the often lengthy waiting lists to manage demand.
Katherine E. Harding, David A. Snowdon, Luke Prendergast, Annie K. Lewis, Bridie Kent, Sandy F. Leggat, Nicholas F. Taylor   +6 more
doaj   +1 more source

The unrecognized role of fidelity in effectiveness-implementation hybrid trials: simulation study and guidance for implementation researchers

BMC Medical Research Methodology, 2023
Background Effectiveness-implementation hybrid designs are a relatively new approach to evaluate efficacious interventions in real-world settings while concurrently gathering information on the implementation.
Diana Trutschel, Catherine Blatter, Michael Simon, Daniela Holle, Sven Reuther, Thekla Brunkert   +5 more
doaj   +1 more source

Adapting and pilot testing an HIV and intersectional stigma reducing intervention for Dominican Republic healthcare contexts: Protocol for translational research

Contemporary Clinical Trials Communications, 2022
Background: This protocol details the adaptation and pilot testing of the Finding Respect and Ending Stigma around HIV (FRESH) intervention in Dominican Republic.
Henna Budhwani, Robert Paulino-Ramírez, John Waters, Christyenne L. Bond, Ingrid Ruiz, Dustin M. Long, Nelson Varas-Díaz, Sylvie Naar, Laura Nyblade, Janet M. Turan   +9 more
doaj   +1 more source