Results 21 to 30 of about 6,729 (263)

Effects of a free school breakfast programme on school attendance, achievement, psychosocial function, and nutrition: a stepped wedge cluster randomised trial

BMC Public Health, 2010
Background Approximately 55,000 children in New Zealand do not eat breakfast on any given day. Regular breakfast skipping has been associated with poor diets, higher body mass index, and adverse effects on children's behaviour and academic performance ...
Maddison Ralph, Michie Jo, Jiang Yannan, Gorton Delvina, Turley Maria, Ni Mhurchu Cliona, Hattie John   +6 more
doaj   +1 more source

Evaluating the performance of Bayesian and restricted maximum likelihood estimation for stepped wedge cluster randomized trials with a small number of clusters

BMC Medical Research Methodology, 2022
Background Stepped wedge trials are an appealing and potentially powerful cluster randomized trial design. However, they are frequently implemented with a small number of clusters.
Kelsey L. Grantham, Jessica Kasza, Stephane Heritier, John B. Carlin, Andrew B. Forbes   +4 more
doaj   +1 more source

Influence of cluster‐period cells in stepped wedge cluster randomized trials

Biometrical Journal, 2022
AbstractStepped wedge cluster randomized trials (SWCRT) are increasingly used for the evaluation of complex interventions in health services research. They randomly allocate treatments to clusters that switch to intervention under investigation at variable time points without returning to control condition. The resulting unbalanced allocation over time
Philipp Mildenberger, Jochem König
openaire   +4 more sources

Novel Ordered Stepped-Wedge Cluster Trial Designs for Detecting Ebola Vaccine Efficacy Using a Spatially Structured Mathematical Model.

PLoS Neglected Tropical Diseases, 2016
BackgroundDuring the 2014 Ebola virus disease (EVD) outbreak, policy-makers were confronted with difficult decisions on how best to test the efficacy of EVD vaccines.
Ibrahim Diakite, Eric Q Mooring, Gustavo E Velásquez, Megan B Murray   +3 more
doaj   +1 more source

Co-creation using crowdsourcing to promote PrEP adherence in China: study protocol for a stepped-wedge randomized controlled trial

BMC Public Health, 2022
Background Adherent pre-exposure prophylaxis (PrEP) uptake can prevent HIV infections. Despite the high HIV incidence, Chinese key populations have low PrEP uptake and adherence.
Yongjie Sha, Chunyan Li, Yuan Xiong, Aniruddha Hazra, Jonathan Lio, Ivy Jiang, Haojie Huang, Jared Kerman, Jannelle Molina, Linghua Li, Ke Liang, Dandan Gong, Quanmin Li, Songjie Wu, Renslow Sherer, Joseph D. Tucker, Weiming Tang   +16 more
doaj   +1 more source

Improving outcomes after pediatric cardiac arrest – the ICU-Resuscitation Project: study protocol for a randomized controlled trial

Trials, 2018
Background Quality of cardiopulmonary resuscitation (CPR) is associated with survival, but recommended guidelines are often not met, and less than half the children with an in-hospital arrest will survive to discharge.
Ron W. Reeder, Alan Girling, Heather Wolfe, Richard Holubkov, Robert A. Berg, Maryam Y. Naim, Kathleen L. Meert, Bradley Tilford, Joseph A. Carcillo, Melinda Hamilton, Matthew Bochkoris, Mark Hall, Tensing Maa, Andrew R. Yates, Anil Sapru, Robert Kelly, Myke Federman, J. Michael Dean, Patrick S. McQuillen, Deborah Franzon, Murray M. Pollack, Ashley Siems, John Diddle, David L. Wessel, Peter M. Mourani, Carleen Zebuhr, Robert Bishop, Stuart Friess, Candice Burns, Shirley Viteri, David A. Hehir, R. Whitney Coleman, Tammara L. Jenkins, Daniel A. Notterman, Robert F. Tamburro, Robert M. Sutton, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN)   +36 more
doaj   +1 more source

Planning stepped wedge cluster randomized trials to detect treatment effect heterogeneity

Statistics in Medicine, 2023
Stepped wedge design is a popular research design that enables a rigorous evaluation of candidate interventions by using a staggered cluster randomization strategy. While analytical methods were developed for designing stepped wedge trials, the prior focus has been solely on testing for the average treatment effect.
Fan Li, Xinyuan Chen, Zizhong Tian, Rui Wang, Patrick J. Heagerty   +4 more
openaire   +3 more sources

Effect and associated factors of a clinical pharmacy model in the incidence of medication errors (EACPharModel) in the Hospital Pablo Tobón Uribe: study protocol for a stepped wedge randomized controlled trial (NCT03338725)

Trials, 2020
Background According to WHO, medication error (ME) is a subject that requires attention at all levels of care to reduce severe and preventable damage related to medication use.
J. Granados, A. Salazar-Ospina, J. P. Botero-Aguirre, A. F. Valencia-Quintero, N. Ortiz, P. Amariles   +5 more
doaj   +1 more source

Improving time to palliative care review with predictive modeling in an inpatient adult population: study protocol for a stepped-wedge, pragmatic randomized controlled trial

Trials, 2021
Background Palliative care is a medical specialty centered on improving the quality of life (QOL) of patients with complex or life-threatening illnesses.
Patrick M. Wilson, Lindsey M. Philpot, Priya Ramar, Curtis B. Storlie, Jacob Strand, Alisha A. Morgan, Shusaku W. Asai, Jon O. Ebbert, Vitaly D. Herasevich, Jalal Soleimani, Brian W. Pickering   +10 more
doaj   +1 more source

Five questions to consider before conducting a stepped wedge trial [PDF]

Trials, 2015
Researchers should consider five questions before starting a stepped wedge trial. Why are you planning one? Researchers sometimes think that stepped wedge trials are useful when there is little doubt about the benefit of the intervention being tested. However, if the primary reason for an intervention is to measure its effect, without equipoise there ...
Hargreaves, JR, Copas, AJ, Beard, E, Osrin, D, Lewis, JJ, Davey, C, Thompson, JA, Baio, G, Fielding, KL, Prost, A   +9 more
openaire   +5 more sources