Results 81 to 90 of about 1,848 (189)

Expanding the scope of pediatric epilepsy surgery: Access, indications, and outcomes in a modern cohort

Epilepsia Open, EarlyView.
Abstract Objective Expanded indications, diagnostic tools, and treatment options have transformed the landscape of modern pediatric epilepsy surgery. Published real‐world experiences from large surgical cohorts are still needed. To close this gap, we evaluated access, indications, treatment, and outcomes in a contemporary pediatric epilepsy surgery ...
John R. McLaren, William Muñoz, Hunki Kwon, Alexandra L. Geffrey, Pranav Nanda, Ronald Thibert, Lily Grossmann, Steven Stufflebeam, Camilo Jaimes, Britt Carlson Emerton, Kristopher T. Kahle, R. Mark Richardson, Catherine J. Chu   +12 more
wiley   +1 more source

Dynamic network connectivity analysis to identify the epileptogenic zones based on stereo-electroencephalography

Frontiers in Computational Neuroscience, 2016
ObjectivesAccurate localization of the epileptogenic zones (EZs) is essential for the successful surgical treatment of the refractory focal epilepsy. The aim of the present study is to investigate whether a dynamic network connectivity analysis based on ...
Junwei Mao, Xiao-Lai Ye, Yong-Hua Li, Pei-Ji Liang, Ji-Wen Xu, Pu-Ming Zhang   +5 more
doaj   +1 more source

Excitatory neurons and astrocytes‐specific dysregulation and aberrant interactions are vulnerable to FCDI as suggested by single‐cell spatial transcriptomics

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
• Excitatory neurons and astrocytes show marked alterations in the single‐cell spatial transcriptomic atlas of epileptogenic cortex from patients with focal cortical dysplasia type I (FCDI). • The CBLN2high excitatory neuron subtype may be associated with neuronal hyperexcitability and cortical development in FCDI.
Yaqian Zhang, Qihang Zou, Yingying Liu, Yinchao Li, Yubao Fang, Tiancai Huang, Jiabin Yu, Lisen Sui, Dezhi Cao, Liemin Zhou   +9 more
wiley   +1 more source

Attention and Executive Functions Are the Most Vulnerable Cognitive Domains in Patients With Drug‐Resistant Epilepsy Prior to Neurostimulation Therapy

Brain and Behavior, Volume 16, Issue 4, April 2026.
More than one‐third of the patients with drug‐resistant epilepsy (DRE) referred for neurostimulation therapies exhibited cognitive impairment across all four assessed domains. Deficits in attention and executive functions were the most prevalent and severe, affecting 66% of the cohort.
Niina Lähde, Pabitra Basnyat, Hanna Lehtinen, Eija Rosti‐Otajärvi, Leena Kämppi, Jukka Peltola   +5 more
wiley   +1 more source

Cortico-Cortical Evoked Potentials in Children With Tuberous Sclerosis Complex Using Stereo-Electroencephalography

Frontiers in Neurology, 2019
Objectives: Patients with tuberous sclerosis complex (TSC) present multiple cortical tubers in the brain, which are responsible for epilepsy. It is still difficult to localize the epileptogenic tuber.
Xiaoman Yu, Ping Ding, Liu Yuan, Juncheng Zhang, Shuangshuang Liang, Shaohui Zhang, Na Liu, Shuli Liang   +7 more
doaj   +1 more source

Proceedings of Science in the House [PDF]

, 2016
Celebrating its 5th anniversary, this year's Science in the House exhibition was a most memorable occasion. The event was held on Thursday 29th September at 11:00 am in the main foyer of the Parliament Building in Valletta.
Magri, David C., Science in the House, University of Malta Research Trust (RIDT)   +2 more
core  

Response: Temporal encephalocele and epileptogenesis—Reflections of MRI metrics of brain parenchymal tethering

Epilepsia, EarlyView.
Efstathios Kondylis, Neha Sara John, Baltazar Zavala, Marina Feldman, Richard Rammo, Imad Najm, William Bingaman, Demitre Serletis, Juan Bulacio   +8 more
wiley   +1 more source

Scalp‐negative medial temporal interictal epileptic discharges alter large‐scale brain networks: A simultaneous high‐density electroencephalographic and intracranial electroencephalographic study

Epilepsia, Volume 67, Issue 4, Page 1992-2006, April 2026.
Abstract Objective Interictal epileptiform discharges (IEDs) observed on scalp electroencephalography (EEG) serve as a diagnostic hallmark of epilepsy. However, only a small fraction of IEDs recorded by intracranial EEG (iEEG) are detectable on the scalp; the vast majority remain invisible on scalp recordings.
Nicolas Roehri, Pia De Stefano, Laurent Spinelli, Renaud Marquis, Stanislas Lagarde, Shahan Momjian, Margitta Seeck, Serge Vulliemoz   +7 more
wiley   +1 more source

Clinical outcomes and learning curve of MRgLITT system for drug‐resistant epilepsy in China: A single‐center retrospective study

Epilepsia Open, Volume 11, Issue 2, Page 475-487, April 2026.
Abstract Objective Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique that allows for real‐time magnetic resonance imaging (MRI) monitoring and precise ablation of epileptogenic lesions. This study reports our initial clinical experience with a domestically developed MRgLITT system in patients with ...
Sichang Chen, Yang Dai, Xiaotong Fan, Yihe Wang, Penghu Wei, Yongzhi Shan, Guoguang Zhao   +6 more
wiley   +1 more source

Identification of the epileptogenic zone of temporal lobe epilepsy from stereo-electroencephalography signals: A phase transfer entropy and graph theory approach

NeuroImage: Clinical, 2017
The aim of this research is to apply an approach based on phase transfer entropy (PTE) and graph theory to study the interactions between the stereo-electroencephalography (SEEG) activities recorded in multilobar origin, in order to evaluate their ...
Meng-yang Wang, Jing Wang, Jian Zhou, Yu-guang Guan, Feng Zhai, Chang-qing Liu, Fei-fei Xu, Yi-xian Han, Zhao-fen Yan, Guo-ming Luan   +9 more
doaj   +1 more source